SCHEMBL647576

SCHEMBL647576

N#Cc1cccnc1O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30597285 1.00
Bromide SCHEMBL1820392 0.98 LRRK2 (0.43)
Phosphoric Acid SCHEMBL27485883 0.90 ELANE (0.39)
Butane SCHEMBL28205932 0.90 HPGD (0.45)
SCHEMBL5408960 0.77
SCHEMBL31267979 0.76 CNR2 (0.49)
SCHEMBL29533314 0.74 LRRK2 (0.46)
SCHEMBL18611 0.74 LRRK2 (0.46)
SCHEMBL196578 0.73
SCHEMBL2642118 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110734398-B New preparation method of 2-chloronicotinic acid 江苏汉阔生物有限公司 2023-06-02 CN claimed
CN-110734398-A process for preparing 2-chloronicotinic acid 江苏汉阔生物有限公司 2020-01-31 CN claimed
US-8119563-B2 N-substituted azacycles FMC CORPORATION (US) 2012-02-21 US claimed
US-20090215821-A1 N-Substituted Azacycles FMC CORPORATION 2009-08-27 US claimed
CN-100475791-C Method for preparing 6-hydroxyl-3-cyanogen pyridine SHANDONG INST LIGHT INDUSTRY (CN) 2009-04-08 CN claimed
EP-1673083-A4 N-SUBSTITUTED AZACYCLES BAYER CROPSCIENCE AG (DE) 2008-12-17 EP claimed
CN-101270082-A Method for preparing 6-hydroxyl-3-cyanogen pyridine SHANDONG INST LIGHT INDUSTRY (CN) 2008-09-24 CN claimed
EP-1673083-A2 N-SUBSTITUTED AZACYCLES FMC CORPORATION (US) 2006-06-28 EP claimed
WO-2005036961-A2 N-SUBSTITUTED AZACYCLES FMC CORPORATION (US) 2005-04-28 WO claimed
CN-1326937-A 3-cyano-3-hydroxy pyridine phosphate ester and its synthetic method and use SHANGHAI INST ORGANIC CHEM (CN) 2001-12-19 CN claimed
CN-114585360-B Methods of using the same for treating epilepsy 特维娜有限公司 2025-04-29 CN disclosed
US-20250099448-A1 HETEROCYCLIC COMPOUNDS HOFFMANN-LA ROCHE INC. (US) 2025-03-27 US disclosed
US-20250074909-A1 AMINOTRIAZOLOPYRIDINES AS KINASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2025-03-06 US disclosed
US-20250049772-A1 PIPERIDINYL-3-(ARYLOXY)PROPANAMIDES AND PROPANOATES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2025-02-13 US disclosed
US-12157733-B2 Aminotriazolopyridines as kinase inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2024-12-03 US disclosed
US-4058533-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1977-11-15 US disclosed
US-4046896-A 1-Methyl-2-(pyridyl-oxymethyl)-5-nitro-imidazoles HOECHST AKTIENGESELLSCHAFT (DT) 1977-09-06 US disclosed
US-4014888-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1977-03-29 US disclosed
US-4009174-A VASODILATORS THE BOOTS COMPANY LIMITED (EN) 1977-02-22 US disclosed
US-3956338-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1976-05-11 US disclosed