Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 5/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 15/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5117110 | 0.87 | AVPR2 (0.47) | AVPR1AAVPR2 | |
| SCHEMBL5428068 | 0.84 | AVPR1A (0.41) | AVPR1AAVPR2 | |
| SCHEMBL5111755 | 0.83 | AVPR2 (0.51) | AVPR1AAVPR2 | |
| SCHEMBL5110450 | 0.81 | AVPR2 (0.42) | AVPR1AAVPR2 | |
| SCHEMBL6210294 | 0.80 | AVPR1A (0.41) | AVPR1AAVPR2 | |
| SCHEMBL5118045 | 0.78 | AVPR1A (0.62) | AVPR1AAVPR2 | |
| SCHEMBL6483323 | 0.76 | AVPR1A (0.49) | AVPR1AAVPR2 | |
| SCHEMBL5835151 | 0.76 | AVPR1A (0.42) | AVPR1AAVPR2 | |
| SCHEMBL5787330 | 0.75 | AVPR1A (0.47) | AVPR1AAVPR2 | |
| SCHEMBL6628771 | 0.75 | AVPR2 (0.58) | AVPR1AAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6977254-B2 | Hydroxy cyclohexenyl phenyl carboxamides tocolytic oxytocin receptor antagonists | WYETH (US) | 2005-12-20 | — | — | US | claimed |
| US-6977254-B2 | Hydroxy cyclohexenyl phenyl carboxamides tocolytic oxytocin receptor antagonists | WYETH (US) | 2005-12-20 | — | — | US | disclosed |