Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.54 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.53 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.53 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.53 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.53 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.53 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.53 |
| ▸ | ACP3 | P15309 | 2/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 4/20 | 0.49 |
| ▸ | PPARA | Q07869 | 3/20 | 0.49 |
| ▸ | FPR2 | P25090 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.46 |
| ▸ | AGXT | P21549 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6472838 | 0.88 | PSEN1 (0.55) | FFAR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL28858320 | 0.85 | ACP3 (0.63) | ACP3PPARGPPARAEPHX2 | |
| SCHEMBL6475463 | 0.84 | PSEN1 (0.59) | FFAR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL28209100 | 0.83 | PPARG (0.58) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6477508 | 0.83 | PSEN1 (0.54) | FFAR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6472107 | 0.82 | PSEN1 (0.79) | FFAR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6472632 | 0.82 | PSEN1 (0.63) | FFAR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6472628 | 0.82 | PSEN1 (0.63) | FFAR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6473844 | 0.80 | PSEN1 (0.52) | FFAR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6477785 | 0.79 | PSEN1 (0.54) | FFAR1PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005110963-A1 | (BIPHENYL-3-YL)-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF AND THEIR USE IN THERAPY | CELLZOME AG (DE) | 2005-11-24 | — | — | WO | claimed |
| WO-2005110963-A1 | (BIPHENYL-3-YL)-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF AND THEIR USE IN THERAPY | CELLZOME AG (DE) | 2005-11-24 | — | — | WO | disclosed |