Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 9/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.41 |
| ▸ | NTRK2 | Q16620 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6482629 | 0.90 | F2 (0.55) | F2NPC1RAB9ASMN1; SMN2HDAC1 | |
| Hydrochloric Acid SCHEMBL6474728 | 0.89 | F2 (0.55) | F2NPC1RAB9ASMN1; SMN2HDAC1 | |
| Hydrochloric Acid SCHEMBL6485385 | 0.88 | F2 (0.49) | F2NPC1RAB9ASMN1; SMN2HDAC1 | |
| Hydrochloric Acid SCHEMBL6475613 | 0.86 | F2 (0.45) | F2NPC1RAB9ASMN1; SMN2NTRK1 | |
| SCHEMBL6474788 | 0.86 | F2 (0.55) | F2NPC1RAB9AHDAC1 | |
| SCHEMBL6485333 | 0.84 | NTRK1 (0.53) | F2NPC1RAB9ASMN1; SMN2NTRK1 | |
| Hydrochloric Acid SCHEMBL6483579 | 0.83 | F2 (0.46) | F2NPC1RAB9ASMN1; SMN2HDAC1 | |
| SCHEMBL6484207 | 0.83 | F2 (0.45) | F2NPC1RAB9ASMN1; SMN2HDAC1 | |
| SCHEMBL6475172 | 0.82 | POLB (0.45) | F2NPC1RAB9ASMN1; SMN2HDAC1 | |
| SCHEMBL6485973 | 0.82 | KDM4E (0.47) | F2NPC1RAB9ASMN1; SMN2NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6855713-B2 | Benzimidazole derivatives, a process for their manufacture and use as a medicine | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2005-02-15 | — | — | US | claimed |