SCHEMBL6478652

SCHEMBL6478652

[c]1nnc(CNC2CC2)s1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.30
HTT P42858 1/20 0.30
MEN1 O00255 1/20 0.30
RAB9A P51151 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8629930 0.71
SCHEMBL10729253 0.64
SCHEMBL8631536 0.63
SCHEMBL423025 0.63
SCHEMBL6489017 0.63
SCHEMBL3480924 0.61 KDM1A (0.53) MEN1RAB9AKMT2A
SCHEMBL11353355 0.60
SCHEMBL1028444 0.60
SCHEMBL8626433 0.60
SCHEMBL4173347 0.59 PDE10A (0.36) MEN1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6858605-B2 Substituted 2,3-benzodiazepine derivatives IVAX DRUG RESEARCH INSTITUTE, LTD. (HU) 2005-02-22 US claimed