Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 19/20 | 0.46 |
| ▸ | RAMP1 | O60894 | 3/20 | 0.46 |
| ▸ | CALCA | P06881 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6478705 | 1.00 | CALCRL (0.46) | CALCRLRAMP1CALCACYP3A4 | |
| SCHEMBL6485140 | 0.90 | CALCRL (0.44) | CALCRLRAMP1CALCACYP3A4 | |
| SCHEMBL6485145 | 0.90 | CALCRL (0.44) | CALCRLRAMP1CALCACYP3A4 | |
| SCHEMBL6477584 | 0.90 | CALCRL (0.59) | CALCRLRAMP1CALCACYP3A4 | |
| SCHEMBL6479368 | 0.90 | CALCRL (0.47) | CALCRLRAMP1CALCACYP3A4 | |
| SCHEMBL6477591 | 0.90 | CALCRL (0.59) | CALCRLRAMP1CALCACYP3A4 | |
| SCHEMBL6479371 | 0.90 | CALCRL (0.47) | CALCRLRAMP1CALCACYP3A4 | |
| SCHEMBL6477892 | 0.89 | CALCRL (0.44) | CALCRLRAMP1CALCACYP3A4 | |
| SCHEMBL6477898 | 0.89 | CALCRL (0.44) | CALCRLRAMP1CALCACYP3A4 | |
| SCHEMBL6478677 | 0.89 | CALCRL (0.53) | CALCRLRAMP1CALCACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6949541-B2 | Substituted piperidines, medicaments containing these compounds, and methods for the production thereof | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2005-09-27 | — | — | US | claimed |