SCHEMBL6480296

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6480262	0.90	TP53 (0.46)	PSMB8CREBBPCA12CA2CA7
	SCHEMBL6479841	0.86	KDM4E (0.41)	CA9KDM4EALDH1A1HDAC6HPGD
	SCHEMBL1390900	0.81	PSMB8 (0.50)	PSMB8CREBBPCA12CA2CA7
	SCHEMBL12432252	0.77	PSMB8 (0.46)	PSMB8CREBBPCA12CA2CA7
	SCHEMBL5031812	0.77	HDAC6 (0.54)	PSMB8CREBBPCA12CA2CA7
	SCHEMBL15159374	0.76	PSMB8 (0.43)	PSMB8CREBBPCA12CA2CA7
	SCHEMBL6090295	0.76	PSMB8 (0.54)	PSMB8CREBBPCA12CA2CA7
	SCHEMBL28125379	0.76	PSMB8 (0.54)	PSMB8CREBBPCA12CA2CA7
	SCHEMBL10290842	0.76	HDAC6 (0.50)	PSMB8CREBBPCA12CA2CA7
	SCHEMBL31683272	0.75	HDAC6 (0.68)	PSMB8CREBBPCA12CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.