Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.67 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.67 |
| ▸ | ELANE | P08246 | 11/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6482180 | 0.99 | CHRM2 (0.66) | CHRM2CHRM1ELANECHRM3ADRB2 | |
| Hydrochloric Acid SCHEMBL5961409 | 0.99 | CHRM2 (0.66) | CHRM2CHRM1ELANECHRM3ADRB2 | |
| SCHEMBL2167828 | 0.91 | CHRM2 (0.77) | CHRM2CHRM1ELANECHRM3ADRB2 | |
| Hydrochloric Acid SCHEMBL5961415 | 0.91 | CHRM2 (0.57) | CHRM2CHRM1ELANECHRM3ADRB2 | |
| SCHEMBL7758391 | 0.89 | CHRM2 (0.72) | CHRM2CHRM1CHRM3ADRB2CHRM5 | |
| SCHEMBL2167563 | 0.89 | CHRM2 (0.72) | CHRM2CHRM1CHRM3ADRB2CHRM5 | |
| SCHEMBL2168552 | 0.89 | CHRM2 (0.80) | CHRM2CHRM1CHRM3ADRB2CHRM5 | |
| SCHEMBL2167951 | 0.89 | CHRM2 (0.80) | CHRM2CHRM1CHRM3ADRB2CHRM5 | |
| Hydrochloric Acid SCHEMBL6473184 | 0.88 | CHRM2 (0.80) | CHRM2CHRM1ELANECHRM3ADRB2 | |
| Hydrochloric Acid SCHEMBL6474425 | 0.88 | CHRM2 (0.67) | CHRM2CHRM1ELANECHRM3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6858650-B1 | For therapy of urinary incontinence | SCHWARZ PHARMA AG (DE) | 2005-02-22 | — | — | US | disclosed |