SCHEMBL648167

SCHEMBL648167

FC1(Cl)[CH]CC1(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7683528 0.79
SCHEMBL424149 0.72
SCHEMBL6216231 0.64
SCHEMBL21802 0.62
SCHEMBL23386 0.62
SCHEMBL7061079 0.60
SCHEMBL14118553 0.59
SCHEMBL2904952 0.59
SCHEMBL4131162 0.59
SCHEMBL10564930 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6077859-A Pyrazoles PFIZER INC. (US) 2000-06-20 US claimed
EP-0959071-A1 1-Aryl-4-cycloalk(en)ylpyrazoles as antiparasitic agents PFIZER INC. (US) 1999-11-24 EP claimed
EP-0253175-B1 SUBSTITUTED FURAZANS BAYER AG (DE) 1992-12-30 EP claimed
US-4853397-A MITICIDES BAYER AKTIENGESELLSCHAFT (DE) 1989-08-01 US claimed
EP-0253175-A2 Substituted furazans BAYER AG (DE) 1988-01-20 EP claimed
US-20240150612-A1 SILICONE COATING AGENT COMPOSITION AND ARTICLE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-05-09 US disclosed
EP-4299683-A1 SILICONE COATING AGENT COMPOSITION AND ARTICLE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-01-03 EP disclosed
CN-113402911-A Silicone coating agent composition and article 信越化学工业株式会社 2021-09-17 CN disclosed
US-9212348-B2 Method for producing hematopoietic stem cells using pyrazole compounds NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-12-15 US disclosed
EP-2647629-B1 PYRAZOLE COMPOUNDS HAVING THERAPEUTIC EFFECT ON MULTIPLE MYELOMA NISSAN CHEMICAL IND LTD (JP) 2015-06-17 EP disclosed
CN-103237793-B Pyrazole compound having therapeutic effect on multiple myeloma NISSAN CHEMICAL IND LTD 2015-06-10 CN disclosed
US-20140057353-A1 METHOD FOR PRODUCING HEMATOPOIETIC STEM CELLS USING PYRAZOLE COMPOUNDS REPROCELL INCORPORATED (JP) 2014-02-27 US disclosed
EP-2151437-A1 ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PEST CONTROL AGENT Nissan Chemical Industries, Ltd. (JP) 2010-02-10 EP disclosed
EP-2139874-A2 ISOXAZOLINE COMPOUNDS AND THEIR USE IN PEST CONTROL Sumitomo Chemical Company, Limited (JP) 2010-01-06 EP disclosed
WO-2008126665-A2 ISOXAZOLINE COMPOUNDS AND THEIR USE IN PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-10-23 WO disclosed
US-6077859-A Pyrazoles PFIZER INC. (US) 2000-06-20 US disclosed
EP-0959071-A1 1-Aryl-4-cycloalk(en)ylpyrazoles as antiparasitic agents PFIZER INC. (US) 1999-11-24 EP disclosed
EP-0253175-B1 SUBSTITUTED FURAZANS BAYER AG (DE) 1992-12-30 EP disclosed
US-4853397-A MITICIDES BAYER AKTIENGESELLSCHAFT (DE) 1989-08-01 US disclosed
EP-0253175-A2 Substituted furazans BAYER AG (DE) 1988-01-20 EP disclosed