Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6481991 | 1.00 | GAA (0.48) | GAAMAPTUSP2RECQLHTT | |
| SCHEMBL6356833 | 0.89 | GAA (0.50) | GAAMAPTUSP2RECQLHTT | |
| SCHEMBL6356830 | 0.89 | GAA (0.50) | GAAMAPTUSP2RECQLHTT | |
| SCHEMBL4706697 | 0.88 | ADORA1 (0.59) | GAAMAPTUSP2RECQLHTT | |
| SCHEMBL4706693 | 0.88 | ADORA1 (0.59) | GAAMAPTUSP2RECQLHTT | |
| SCHEMBL8128491 | 0.85 | PDE2A (0.54) | GAAMAPTADORA1 | |
| SCHEMBL8126523 | 0.85 | PDE2A (0.54) | GAAMAPTADORA1 | |
| SCHEMBL8126108 | 0.85 | PDE2A (0.54) | GAAMAPTADORA1 | |
| SCHEMBL6355685 | 0.84 | PDE4A (0.41) | GAAMAPT | |
| SCHEMBL6355684 | 0.84 | PDE4A (0.41) | GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6878715-B1 | Therapeutic compounds for inhibiting interleukin-12 signals and method for using same | CELL THERAPEUTICS, INC. (US) | 2005-04-12 | — | — | US | disclosed |