Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6484132 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1LMNATHRBKMT2A | |
| SCHEMBL6474372 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1LMNATHRBKMT2A | |
| SCHEMBL6476214 | 0.99 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1LMNATHRBKMT2A | |
| SCHEMBL6475681 | 0.91 | LPAR1 (0.46) | SMN1; SMN2ALDH1A1LMNATHRBLPAR1 | |
| SCHEMBL6485778 | 0.91 | LPAR1 (0.46) | SMN1; SMN2ALDH1A1LMNATHRBLPAR1 | |
| SCHEMBL6485593 | 0.91 | LPAR1 (0.46) | SMN1; SMN2ALDH1A1LMNATHRBLPAR1 | |
| SCHEMBL6481625 | 0.89 | LPAR1 (0.45) | SMN1; SMN2ALDH1A1LMNATHRBKMT2A | |
| SCHEMBL6483516 | 0.88 | KMT2A (0.42) | SMN1; SMN2ALDH1A1LMNATHRBKMT2A | |
| SCHEMBL6483627 | 0.88 | KMT2A (0.42) | SMN1; SMN2ALDH1A1LMNATHRBKMT2A | |
| SCHEMBL6475778 | 0.87 | KMT2A (0.41) | SMN1; SMN2ALDH1A1LMNATHRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6939888-B2 | 1-H-3-arylpirrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2005-09-06 | — | — | US | disclosed |
| US-6472419-B1 | 1-H-3-aryl-pyrrolidine-2, 4-dione derivatives as pest-control agents | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | disclosed |