Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 18/20 | 0.71 |
| ▸ | FPR3 | P25089 | 1/20 | 0.51 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6482552 | 1.00 | CCR1 (0.71) | CCR1FPR3GPR65GPR35PTGDR2 | |
| SCHEMBL6482554 | 1.00 | CCR1 (0.71) | CCR1FPR3GPR65GPR35PTGDR2 | |
| SCHEMBL4587784 | 0.90 | CCR1 (0.68) | CCR1FPR3GPR65GPR35PTGDR2 | |
| SCHEMBL4587791 | 0.90 | CCR1 (0.68) | CCR1FPR3GPR65GPR35PTGDR2 | |
| SCHEMBL4587787 | 0.90 | CCR1 (0.68) | CCR1FPR3GPR65GPR35PTGDR2 | |
| SCHEMBL4589152 | 0.89 | CCR1 (0.74) | CCR1FPR3GPR65GPR35PTGDR2 | |
| SCHEMBL4589147 | 0.89 | CCR1 (0.74) | CCR1FPR3GPR65GPR35PTGDR2 | |
| SCHEMBL4589157 | 0.89 | CCR1 (0.74) | CCR1FPR3GPR65GPR35PTGDR2 | |
| SCHEMBL4587553 | 0.87 | CCR1 (0.72) | CCR1FPR3GPR65GPR35PTGDR2 | |
| SCHEMBL4587558 | 0.87 | CCR1 (0.72) | CCR1FPR3GPR65GPR35PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101090723-A | Piperazine urea derivatives for the treatment of endometriosis | SCHERING AG (DE) | 2007-12-19 | — | — | CN | disclosed |
| US-6977258-B2 | Piperazine derivatives and their use as anti-inflammatory agents | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-12-20 | — | — | US | disclosed |