SCHEMBL6483177

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6477495	0.95	PDE5A (0.78)	PDE5APDE3BPDE3A
	SCHEMBL6475468	0.93	PDE5A (0.85)	PDE5AHDAC1HDAC2HDAC6PDE3B
	SCHEMBL6643381	0.93	PDE5A (0.81)	PDE5AHDAC1HDAC2HDAC6PDE3B
	SCHEMBL6642932	0.92	PDE5A (0.81)	PDE5AHDAC1HDAC2HDAC6PDE3B
	SCHEMBL6641140	0.91	PDE5A (0.81)	PDE5AHDAC1HDAC2HDAC6PDE3B
	SCHEMBL22028347	0.91	PDE5A (1.00)	PDE5AHDAC1HDAC2HDAC6PDE3B
	SCHEMBL7055096	0.89	PDE5A (0.76)	PDE5AHDAC1HDAC2HDAC6PDE3B
	SCHEMBL6639075	0.89	PDE5A (0.86)	PDE5AHDAC1HDAC2HDAC6PDE3B
	SCHEMBL6643698	0.89	PDE5A (0.83)	PDE5AHDAC1HDAC2HDAC6PDE3B
	SCHEMBL6641062	0.89	PDE5A (0.75)	PDE5APDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.