Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.69 |
| ▸ | CA2 | P00918 | 1/20 | 0.69 |
| ▸ | MMP1 | P03956 | 1/20 | 0.69 |
| ▸ | MMP2 | P08253 | 1/20 | 0.69 |
| ▸ | MMP9 | P14780 | 1/20 | 0.69 |
| ▸ | MMP8 | P22894 | 1/20 | 0.69 |
| ▸ | MMP13 | P45452 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | F2 | P00734 | 3/20 | 0.62 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.62 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.62 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30732635 | 1.00 | CA1 (0.69) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL22532073 | 0.83 | F2 (0.49) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL30339289 | 0.81 | CA1 (0.69) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL46064 | 0.81 | CA1 (0.69) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL27962904 | 0.81 | CA1 (0.69) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL5810580 | 0.81 | CA1 (0.69) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL8224048 | 0.81 | CA1 (1.00) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL30649118 | 0.80 | KMT2A (0.71) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL4389696 | 0.80 | KMT2A (0.71) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL11514739 | 0.80 | CA1 (0.67) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120040409-A | Preparation method and application of macrolide compound and intermediate compound thereof | 中国科学院昆明植物研究所 | 2025-05-27 | — | — | CN | claimed |
| WO-2024042491-A1 | ORGANIC LAYER COMPRISING REGIONS HAVING DIFFERENT ELECTRONIC PROPERTIES | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2024-02-29 | — | — | WO | claimed |
| CN-115368437-A | Method for solid-phase synthesis of cyclic polypeptide | 深圳市第二人民医院(深圳市转化医学研究院) | 2022-11-22 | — | — | CN | claimed |
| EP-3701065-A1 | SINGLE- AND MIXED-METAL NANOPARTICLES, NANOPARTICLE CONJUGATES, DEVICES FOR MAKING NANOPARTICLES, AND RELATED METHODS OF USE | Montrose Biosystems LLC (US) | 2020-09-02 | — | — | EP | claimed |
| CN-105805426-B | Pipeline runs through device | 上海火克新材料有限公司 | 2017-10-27 | — | — | CN | claimed |
| EP-2496577-A1 | IMIDAZOPYRIDINE DERIVATIVES | Piramal Life Sciences Limited (IN) | 2012-09-12 | — | — | EP | claimed |
| WO-2011055320-A1 | IMIDAZOPYRIDINE DERIVATIVES | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2011-05-12 | — | — | WO | claimed |
| EP-0140886-B1 | FILM BADGE FOR DETERMINING CARBONYL COMPOUNDS | Crystal Diagnostic Systems, Inc. (US) | 1988-09-07 | — | — | EP | claimed |
| EP-0103840-B1 | METHOD FOR PREPARING 1,2,3-TRIHETERO 5-MEMBERED HETEROCYCLIC COMPOUNDS | LEDERLE (JAPAN) LTD. (JP) | 1987-03-04 | — | — | EP | claimed |
| US-4540794-A | Method for preparing 5-mercapto-1,2,3-thiadiazole salts | LEDERLE (JAPAN), LTD. (JP) | 1985-09-10 | — | — | US | claimed |
| EP-4725941-A1 | ARYLAMIDE DERIVATIVE HAVING ANTITUMOR ACTIVITY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2026-04-15 | — | — | EP | disclosed |
| US-20250313574-A1 | SIALIC ACID DERIVATIVES AND METHODS OF USING SAME | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2025-10-09 | — | — | US | disclosed |
| US-12410212-B2 | Cyclic compound having selective KRAS inhibitory effect on HRAS and NRAS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2025-09-09 | — | — | US | disclosed |
| US-12404248-B2 | IRE1 small molecule inhibitors | CORNELL UNIVERSITY (US) | 2025-09-02 | — | — | US | disclosed |
| EP-4603105-A1 | PHARMACEUTICAL COMPOSITION CONTAINING CYCLIC COMPOUND HAVING SELECTIVE KRAS INHIBITORY EFFECT AGAINST HRAS AND NRAS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2025-08-20 | — | — | EP | disclosed |
| EP-1320523-A2 | BRANCHED CHAIN AMINO ACID-DEPENDENT AMINOTRANSFERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | Warner-Lambert Company LLC (US) | 2003-06-25 | — | — | EP | disclosed |
| WO-2002024672-A2 | BRANCHED CHAIN AMINO ACID-DEPENDENT AMINOTRANSFERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | WARNER-LAMBERT COMPANY LLC (US) | 2002-03-28 | — | — | WO | disclosed |
| EP-0103840-B1 | METHOD FOR PREPARING 1,2,3-TRIHETERO 5-MEMBERED HETEROCYCLIC COMPOUNDS | LEDERLE (JAPAN) LTD. (JP) | 1987-03-04 | — | — | EP | disclosed |
| US-4540794-A | Method for preparing 5-mercapto-1,2,3-thiadiazole salts | LEDERLE (JAPAN), LTD. (JP) | 1985-09-10 | — | — | US | disclosed |
| EP-0103840-A2 | Method for preparing 1,2,3-trihetero 5-membered heterocyclic compounds | LEDERLE (JAPAN) LTD. (JP) | 1984-03-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12410212-B2 | Cyclic compound having selective KRAS inhibitory effect on HRAS and NRAS | KRAS, HRAS, NRAS | CA1 3123/4885CA2 2914/4885MMP1 4819/4885 |
| US-20250313574-A1 | SIALIC ACID DERIVATIVES AND METHODS OF USING SAME | NEU1, NEU2, NEU4 | CA1 95/4885CA2 1654/4885MMP1 1187/4885 |
| US-12404248-B2 | IRE1 small molecule inhibitors | XBP1, ERN2, ERN1 | CA1 4652/4885CA2 4217/4885MMP1 4116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.