Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 8/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6485488 | 1.00 | SLC2A1 (0.53) | SLC2A1KCNH2LMNAGAAHTT | |
| SCHEMBL6485492 | 1.00 | SLC2A1 (0.53) | SLC2A1KCNH2LMNAGAAHTT | |
| SCHEMBL5757405 | 0.89 | SLC2A1 (0.59) | SLC2A1KCNH2 | |
| SCHEMBL5757150 | 0.87 | MAPT (0.55) | SLC2A1KCNH2 | |
| SCHEMBL5757406 | 0.87 | MAPT (0.55) | SLC2A1KCNH2 | |
| SCHEMBL5757409 | 0.87 | MAPT (0.55) | SLC2A1KCNH2 | |
| SCHEMBL6498397 | 0.86 | SLC2A1 (0.60) | SLC2A1KCNH2 | |
| SCHEMBL6498402 | 0.86 | SLC2A1 (0.60) | SLC2A1KCNH2 | |
| SCHEMBL6645387 | 0.86 | SLC2A1 (0.60) | SLC2A1KCNH2 | |
| SCHEMBL6497372 | 0.86 | SLC2A1 (0.60) | SLC2A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6911442-B1 | Quinoline derivatives as antibacterials | SMITHKLINE BEECHAM P.L.C. (GB) | 2005-06-28 | — | — | US | claimed |
| US-6911442-B1 | Quinoline derivatives as antibacterials | SMITHKLINE BEECHAM P.L.C. (GB) | 2005-06-28 | — | — | US | disclosed |
| EP-1187828-B1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2004-04-21 | — | — | EP | disclosed |