Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.34 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6486782 | 0.98 | CA14 (0.35) | EPHX1CA14TDP1PDE3BPDE3A | |
| SCHEMBL6497271 | 0.97 | CA14 (0.36) | EPHX1CA14TDP1PDE3BPDE3A | |
| SCHEMBL4914499 | 0.92 | CA14 (0.37) | CA14TDP1HSD11B1DPP4HDAC1 | |
| SCHEMBL1067463 | 0.91 | EPHX1 (0.36) | EPHX1CA14PYGLHSD11B1GAA | |
| SCHEMBL20408347 | 0.89 | CA14 (0.44) | EPHX1CA14TDP1PDE3BPDE3A | |
| SCHEMBL10323856 | 0.89 | CA14 (0.34) | EPHX1CA14HSD11B1GAADPP4 | |
| SCHEMBL4711748 | 0.88 | CA14 (0.39) | CA14TDP1HSD11B1DPP4HDAC1 | |
| SCHEMBL13668663 | 0.87 | MC4R (0.37) | EPHX1CA14PDE3BPDE3APYGL | |
| SCHEMBL1240735 | 0.87 | CA14 (0.34) | CA14TDP1HDAC1HDAC2HDAC6 | |
| SCHEMBL2660428 | 0.87 | CA14 (0.34) | CA14TDP1HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6903107-B1 | Serine protease inhibitor | AKZO NOBEL N.V. (NL) | 2005-06-07 | — | — | US | disclosed |
| EP-1123280-A1 | SERINE PROTEASE INHIBITOR | Akzo Nobel N.V. (NL) | 2001-08-16 | — | — | EP | disclosed |
| WO-2000024718-A1 | SERINE PROTEASE INHIBITOR | AKZO NOBEL N.V. (NL) | 2000-05-04 | — | — | WO | disclosed |