Sugi Predict

Sugi Predict / Compounds / SCHEMBL648738

SCHEMBL648738

SCHEMBL648738

OCP(c1ccccc1)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 4/20 0.45
▸ CYP3A4 P08684 2/20 0.45
▸ TSHR P16473 1/20 0.41
▸ ESR1 P03372 4/20 0.40
▸ ESR2 Q92731 4/20 0.40
▸ ALDH1A1 P00352 2/20 0.33
▸ CA12 O43570 1/20 0.33
▸ CA1 P00915 1/20 0.33
▸ CA2 P00918 1/20 0.33
▸ GLA P06280 1/20 0.33
▸ CA3 P07451 1/20 0.33
▸ CA4 P22748 1/20 0.33
▸ CA9 Q16790 1/20 0.33
▸ CA14 Q9ULX7 1/20 0.33
▸ RECQL P46063 1/20 0.33
▸ BACE1 P56817 1/20 0.32
▸ CALM1 P0DP23 1/20 0.32
▸ HPGD P15428 3/20 0.31
▸ GAA P10253 2/20 0.31
▸ KDM4E B2RXH2 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16005323 0.97 TDP1 (0.43) TDP1CYP3A4TSHRESR1ESR2
SCHEMBL7601693 0.88 TDP1 (0.36) TDP1CYP3A4TSHRESR1ESR2
SCHEMBL7635794 0.80 TDP1 (0.43) TDP1CYP3A4TSHRESR1ESR2
SCHEMBL7601689 0.79 ESR1 (0.32) TDP1CYP3A4ESR1ESR2
SCHEMBL505809 0.78 TDP1 (0.41) TDP1CYP3A4TSHRESR1ESR2
SCHEMBL2973736 0.77 TDP1 (0.45) TDP1CYP3A4TSHRESR1ESR2
SCHEMBL1465059 0.77 TDP1 (0.45) TDP1CYP3A4TSHRESR1ESR2
SCHEMBL23779954 0.76 TDP1 (0.39) TDP1CYP3A4TSHRESR1ESR2
SCHEMBL9518542 0.76 TDP1 (0.39) TDP1CYP3A4TSHRESR1ESR2
SCHEMBL27343 0.75 CYP3A4 (0.50) TDP1CYP3A4TSHRESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 221 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117843679-A Fluorine-containing biphosphine compound and preparation method thereof 四川轻化工大学 2024-04-09 — — CN claimed
CN-116675721-A Carbon propane bridged iron-iron hydrogenase model, and synthetic method and application thereof 桂林师范高等专科学校 2023-09-01 — — CN claimed
CN-116514867-A Monophosphine compound and preparation method thereof 四川轻化工大学 2023-08-01 — — CN claimed
CN-109651446-B Monophosphine-substituted bridged azapropane bridged iron-iron hydrogenase model compound and synthesis method and application thereof 广西师范大学 2021-02-05 — — CN claimed
US-20200385570-A1 POLYCARBONATE COMPOSITIONS BASF SE (DE) 2020-12-10 — — US claimed
EP-3710145-A1 POLYCARBONATE COMPOSITIONS BASF SE (DE) 2020-09-23 — — EP claimed
CN-111328293-A Polycarbonate compositions 巴斯夫欧洲公司 2020-06-23 — — CN claimed
CN-109651446-A A kind of list phosphine replaces bridging azepine propane bridge iron iron hydrogenation catalator object and its synthetic method and application 广西师范大学 2019-04-19 — — CN claimed
US-6476178-B1 Polycarbonate resin composition IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-11-05 — — US claimed
US-12570837-B2 Polycarbonate resin composition and molded article IDEMITSU KOSAN CO., LTD. (JP) 2026-03-10 — — US disclosed
EP-4692233-A1 POLYCARBONATE RESIN COMPOSITION Mitsubishi Engineering-Plastics Corporation (JP) 2026-02-11 — — EP disclosed
EP-3604443-B1 POLYCARBONATE RESIN COMPOSITION AND MOLDED BODY IDEMITSU KOSAN CO (JP) 2025-10-15 — — EP disclosed
US-12398266-B2 Polycarbonate resin composition IDEMITSU KOSAN CO., LTD. (JP) 2025-08-26 — — US disclosed
US-20250205637-A1 GAS SEPARATION MEMBRANE IDEMITSU KOSAN CO., LTD. (JP) 2025-06-26 — — US disclosed
US-4627949-A PHOSPHINE STABILIZER BAYER AKTIENGESELLSCHAFT (DE) 1986-12-09 — — US disclosed
US-RE32046-E PHOSPHINES IN OXETANYL-ALKOXYSILANES OR OXETANYL= =METHYL CARBOXYESTERS, HEAT AND OXIDATION RESISTANCE BAYER AKTIENGESELLSCHAFT (DE) 1985-12-10 — — US disclosed
EP-0143906-A1 Process for preparing stabilized polycarbonate moulded articles by vented injection moulding or vented extrusion moulding BAYER AG (DE) 1985-06-12 — — EP disclosed
EP-0043998-B1 STABILIZER MIXTURES, THEIR USE IN STABILIZING THERMOPLASTIC POLYCARBONATES, AND STABILIZED THERMOPLASTIC POLYCARBONATES BAYER AG (DE) 1984-04-18 — — EP disclosed
US-4367303-A Solutions for stabilizing thermoplastic polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 1983-01-04 — — US disclosed
EP-0043998-A2 Stabilizer mixtures, their use in stabilizing thermoplastic polycarbonates, and stabilized thermoplastic polycarbonates BAYER AG (DE) 1982-01-20 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570837-B2 Polycarbonate resin composition and molded article ERCC1, POT1, BMI1 TDP1 1001/4885CYP3A4 1595/4885TSHR 4407/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.