Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | PRKCI | P41743 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3670301 | 0.88 | OXER1 (0.51) | OXER1FAAHCYP2A6FFAR1CYP1A2 | |
| SCHEMBL31369737 | 0.84 | S1PR1 (0.46) | OXER1S1PR1FAAHCHRNA7CYP2A6 | |
| SCHEMBL5094204 | 0.84 | KDM4E (0.58) | FAAHCHRNA7CYP2A6PRKCITRPV1 | |
| SCHEMBL28839373 | 0.84 | CHRNA7 (0.49) | FAAHCHRNA7CYP2A6HDAC3HDAC4 | |
| SCHEMBL31369499 | 0.81 | CHRNA7 (0.52) | FAAHCHRNA7CYP2A6TRPV1 | |
| SCHEMBL14402849 | 0.80 | PRKCI (0.50) | FAAHCHRNA7CYP2A6PRKCITRPV1 | |
| SCHEMBL30173446 | 0.79 | PRKCI (0.49) | FAAHCHRNA7CYP2A6PRKCITRPV1 | |
| SCHEMBL25186563 | 0.79 | GRIK1 (0.48) | OXER1FAAHCHRNA7CYP2A6PRKCI | |
| SCHEMBL30510384 | 0.79 | GRIK1 (0.48) | OXER1FAAHCHRNA7CYP2A6PRKCI | |
| SCHEMBL25186562 | 0.79 | GRIK1 (0.48) | OXER1FAAHCHRNA7CYP2A6PRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6972296-B2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC. (US) | 2005-12-06 | — | — | US | disclosed |