SCHEMBL648868

SCHEMBL648868

CC(=O)NC(CCN)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.57
KDM4E B2RXH2 1/20 0.57
MAPT P10636 1/20 0.57
THRB P10828 1/20 0.57
ALOX15 P16050 1/20 0.57
NFKB1 P19838 1/20 0.57
PTGS2 P35354 1/20 0.57
THPO P40225 1/20 0.57
RECQL P46063 1/20 0.57
BLM P54132 1/20 0.57
ALDH1A1 P00352 1/20 0.55
GNPAT O15228 2/20 0.50
GABRR1 P24046 2/20 0.46
FOLH1 Q04609 5/20 0.44
ITGB3 P05106 1/20 0.43
ITGA2B P08514 1/20 0.43
RIMKLA Q8IXN7 1/20 0.42
NAALAD2 Q9Y3Q0 1/20 0.42
SIRT6 Q8N6T7 1/20 0.41
SIRT1 Q96EB6 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9800504 1.00 SMN1; SMN2 (0.57) SMN1; SMN2KDM4EMAPTTHRBALOX15
SCHEMBL648867 1.00 SMN1; SMN2 (0.57) SMN1; SMN2KDM4EMAPTTHRBALOX15
SCHEMBL159460 0.88 GNPAT (0.55) SMN1; SMN2KDM4EMAPTTHRBALOX15
SCHEMBL159461 0.88 GNPAT (0.55) SMN1; SMN2KDM4EMAPTTHRBALOX15
SCHEMBL159459 0.88 GNPAT (0.55) SMN1; SMN2KDM4EMAPTTHRBALOX15
SCHEMBL919220 0.86 FOLH1 (0.62) SMN1; SMN2KDM4EMAPTTHRBALOX15
SCHEMBL31002555 0.86 GNPAT (0.54) SMN1; SMN2KDM4EMAPTTHRBALOX15
SCHEMBL20530 0.86 FOLH1 (0.62) SMN1; SMN2KDM4EMAPTTHRBALOX15
SCHEMBL29390797 0.86 GNPAT (0.54) SMN1; SMN2KDM4EMAPTTHRBALOX15
SCHEMBL20529 0.86 FOLH1 (0.62) SMN1; SMN2KDM4EMAPTTHRBALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114134127-A Diaminobutyrate acetyltransferase mutants for the synthesis of ectoin 上海邦林生物科技有限公司 2022-03-04 CN claimed
US-9333232-B2 Methods for treating papilloma virus infection NANOVIR LLC (US) 2016-05-10 US claimed
US-9290551-B2 Compounds for treating papilloma virus infection NANOVIR LLC (US) 2016-03-22 US claimed
WO-2016022664-A1 ANTIVIRAL COMPOUNDS AND METHODS FOR TREATING INFECTIONS CAUSED BY DOUBLE-STRANDED DNA VIRUSES NANOVIR LLC (US) 2016-02-11 WO claimed
US-20150329596-A1 ANTIVIRAL COMPOUNDS AND METHODS FOR TREATING INFECTIONS CAUSED BY DOUBLE-STRANDED DNA VIRUSES THE CURATORS OF THE UNIVERSITY OF MISSOURI 2015-11-19 US claimed
US-20150239943-A1 COMPOUNDS FOR TREATING PAPILLOMA VIRUS INFECTION THE CURATORS OF THE UNIVERSITY OF MISSOURI 2015-08-27 US claimed
US-8993609-B2 Compounds for treating papilloma virus infection NANOVIR, LLC (US) 2015-03-31 US claimed
WO-2014065848-A2 COMPOUNDS FOR TREATING PAPILLOMA VIRUS INFECTION BASHKIN JAMES K (US) 2014-05-01 WO claimed
US-20120225809-A1 COMPOUNDS FOR TREATING PAPILLOMA VIRUS INFECTION NANOVIR, LLC (US) 2012-09-06 US claimed
US-8119677-B2 Polyamides containing amino butyric acid-based building blocks NANOVIR, LLC (US) 2012-02-21 US claimed
CN-101698662-A Artificial synthesis method of 1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid UNIV SHANDONG 2010-04-28 CN claimed
US-20100015084-A1 Compounds for Treating Papilloma Virus Infection NANOVIR, LLC (US) 2010-01-21 US claimed
US-20090306164-A1 Methods for Treating Papilloma Virus Infection NANOVIR, LLC (US) 2009-12-10 US claimed
CN-116987649-B Genetically engineered bacterium for efficiently producing ectoin and preparation and application thereof 山东泓达生物科技有限公司 2025-03-21 CN disclosed
US-12209252-B2 Transduction buffer KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN (NL) 2025-01-28 US disclosed
EP-3954390-B1 TRANSDUCTION BUFFER KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN (NL) 2024-08-07 EP disclosed
CN-101698662-A Artificial synthesis method of 1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid UNIV SHANDONG 2010-04-28 CN disclosed
CN-101698662-A Artificial synthesis method of 1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid UNIV SHANDONG 2010-04-28 CN disclosed
US-20100015084-A1 Compounds for Treating Papilloma Virus Infection NANOVIR, LLC (US) 2010-01-21 US disclosed
US-20090306164-A1 Methods for Treating Papilloma Virus Infection NANOVIR, LLC (US) 2009-12-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120225809-A1 COMPOUNDS FOR TREATING PAPILLOMA VIRUS INFECTION POLI, TLR3, PMAIP1 SMN1; SMN2 4595/4885KDM4E 2048/4885MAPT 2213/4885
US-20150329596-A1 ANTIVIRAL COMPOUNDS AND METHODS FOR TREATING INFECTIONS CAUSED BY DOUBLE-STRANDED DNA VIRUSES POLI, POLL, PCNA SMN1; SMN2 2849/4885KDM4E 2238/4885MAPT 2713/4885
US-20090306164-A1 Methods for Treating Papilloma Virus Infection POLI, VHL, TLR3 SMN1; SMN2 4478/4885KDM4E 2155/4885MAPT 3325/4885
US-20150239943-A1 COMPOUNDS FOR TREATING PAPILLOMA VIRUS INFECTION POLI, TLR3, PMAIP1 SMN1; SMN2 4595/4885KDM4E 2048/4885MAPT 2213/4885
US-20100015084-A1 Compounds for Treating Papilloma Virus Infection POLI, PMAIP1, TLR3 SMN1; SMN2 4689/4885KDM4E 1638/4885MAPT 2258/4885
US-12209252-B2 Transduction buffer STAT3, JAK2, CFTR SMN1; SMN2 3021/4885KDM4E 4597/4885MAPT 1941/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.