Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL646531 | 0.90 | PTPN1 (0.56) | PTPN1PTPN2 | |
| SCHEMBL649552 | 0.90 | PTPN1 (0.56) | PTPN1PTPN2 | |
| SCHEMBL12971426 | 0.90 | PTPN1 (0.53) | PTPN1PTPN2 | |
| SCHEMBL646546 | 0.85 | PTPN1 (0.51) | PTPN1PTPN2 | |
| SCHEMBL647461 | 0.85 | PTPN1 (0.51) | PTPN1PTPN2 | |
| SCHEMBL648366 | 0.81 | PTPN1 (0.55) | PTPN1PTPN2 | |
| SCHEMBL647675 | 0.80 | PTPN1 (0.57) | PTPN1PTPN2 | |
| SCHEMBL648320 | 0.80 | PTPN1 (0.57) | PTPN1PTPN2 | |
| SCHEMBL647796 | 0.80 | PTPN1 (0.55) | PTPN1PTPN2 | |
| SCHEMBL12971497 | 0.80 | PTPN1 (0.55) | PTPN1PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963294-B1 | 1,2,5-THIAZOLIDINE DERIVATIVES USEFUL FOR TREATING CONDITIONS MEDIATED BY PROTEIN TYROSINE PHOSPHATASES (PTPASE) | NOVARTIS AG (CH) | 2012-10-10 | — | — | EP | claimed |
| US-8119665-B2 | Aryl imidazoles and related compounds as C5a receptor modulators | NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) | 2012-02-21 | — | — | US | disclosed |