⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2401894 | 0.77 | — | — | |
| SCHEMBL10915636 | 0.75 | — | — | |
| SCHEMBL11427873 | 0.75 | — | — | |
| SCHEMBL507650 | 0.75 | — | — | |
| SCHEMBL11068868 | 0.73 | — | — | |
| SCHEMBL11334519 | 0.72 | — | — | |
| SCHEMBL9967881 | 0.71 | — | — | |
| SCHEMBL8481662 | 0.71 | — | — | |
| SCHEMBL12468581 | 0.67 | ESR1 (0.32) | — | |
| SCHEMBL11727995 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6903103-B2 | Linear cyclic ureas | LES LABORATORIES SERVIER (FR) | 2005-06-07 | — | — | US | disclosed |
| US-20030229100-A1 | New linear cyclic ureas | PEGLION JEAN-LOUIS (FR) | 2003-12-11 | — | — | US | disclosed |
| US-6566364-B2 | Isomers, hydrates, solvates and addition salts in treatment of endothelial dysfunction disease such as atherosclerosis, dyslipidaemia; antidiabetic agents; heart transplantation; inhibition of nitrogen monoxide synthase and oxidative stress | LES LABORATOIRES SERVIER (FR) | 2003-05-20 | — | — | US | disclosed |
| US-20010009911-A1 | New linear or cyclic ureas | LES LABORATOIRES SERVIER (FR) | 2001-07-26 | — | — | US | disclosed |
| WO-1993011132-A1 | METHOD OF PREPARING THE ANTIBIOTIC CEFACLOR | CIBA-GEIGY AG (CH) | 1993-06-10 | — | — | WO | disclosed |