Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 18/20 | 0.54 |
| ▸ | ICAM1 | P05362 | 18/20 | 0.54 |
| ▸ | ITGAL | P20701 | 18/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6197157 | 0.93 | ITGB2 (0.55) | ITGB2ICAM1ITGALALDH1A1LMNA | |
| SCHEMBL6200179 | 0.91 | ITGB2 (0.60) | ITGB2ICAM1ITGALALDH1A1LMNA | |
| SCHEMBL6197412 | 0.87 | ITGB2 (0.50) | ITGB2ICAM1ITGALALDH1A1LMNA | |
| SCHEMBL6201317 | 0.87 | ITGB2 (0.70) | ITGB2ICAM1ITGALALDH1A1LMNA | |
| SCHEMBL6194824 | 0.87 | ITGB2 (0.62) | ITGB2ICAM1ITGALALDH1A1LMNA | |
| SCHEMBL6197324 | 0.86 | ITGB2 (0.52) | ITGB2ICAM1ITGALALDH1A1LMNA | |
| SCHEMBL6201823 | 0.85 | ITGB2 (0.49) | ITGB2ICAM1ITGALALDH1A1LMNA | |
| SCHEMBL7617894 | 0.84 | ITGB2 (0.42) | ITGB2ICAM1ITGALALDH1A1LMNA | |
| SCHEMBL6199489 | 0.84 | ITGB2 (0.48) | ITGB2ICAM1ITGALALDH1A1LMNA | |
| SCHEMBL6198855 | 0.83 | ITGB2 (0.48) | ITGB2ICAM1ITGALALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6878700-B1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-04-12 | — | — | US | disclosed |