Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NR2E3 | Q9Y5X4 | 2/20 | 0.47 |
| ▸ | NPY2R | P49146 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | F2R | P25116 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | UBE2M | P61081 | 1/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6480891 | 0.89 | NPSR1 (0.50) | GRM4NPSR1NPY2RMAOAMAOB | |
| SCHEMBL6481059 | 0.88 | NPSR1 (0.49) | GRM4NPSR1NPY2RMAOAMAOB | |
| SCHEMBL6492262 | 0.87 | NPSR1 (0.47) | GRM4NPSR1NPY2RMAOAMAOB | |
| SCHEMBL6493898 | 0.87 | GRM4 (0.52) | GRM4NPSR1MAOAMAOBALDH1A1 | |
| SCHEMBL6492402 | 0.85 | NPSR1 (0.46) | GRM4NPSR1NPY2RMAOAMAOB | |
| SCHEMBL6487994 | 0.85 | MEN1 (0.46) | NPSR1HPGDUBE2MDCUN1D1LMNA | |
| SCHEMBL6492666 | 0.84 | NPSR1 (0.45) | GRM4NPSR1NPY2RMAOAMAOB | |
| SCHEMBL6480181 | 0.84 | NPSR1 (0.51) | NPSR1MAOAMAOBHPGDALDH1A1 | |
| SCHEMBL6480935 | 0.83 | NPSR1 (0.50) | NPSR1MAOAMAOBHPGDALDH1A1 | |
| SCHEMBL6489974 | 0.83 | JAK2 (0.43) | NPSR1MAOAMAOBGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050215614-A1 | Substituted indoles and their use as hcv inhibitors | RIGEL PHARMACEUTICALS, INC. (US) | 2005-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215614-A1 | Substituted indoles and their use as hcv inhibitors | IDO1, IDO2, HAVCR2 | GRM4 3740/4885NPSR1 556/4885NR2E3 4427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.