SCHEMBL6490932

SCHEMBL6490932

CC(C)C(=O)N(Oc1cccc(Cl)c1)C(C)C(Cc1ccc(C#N)cc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 19/20 0.47
CNR2 P34972 14/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6490929 0.75 CNR1 (0.57) CNR1CNR2
SCHEMBL3370397 0.75 CNR1 (0.83) CNR1CNR2
SCHEMBL1829125 0.71 CNR1 (0.66) CNR1CNR2
SCHEMBL4689405 0.66 CNR1 (0.54) CNR1CNR2
SCHEMBL3372384 0.66 CNR1 (0.80) CNR1CNR2
SCHEMBL3372387 0.66 CNR1 (0.80) CNR1CNR2
SCHEMBL3374291 0.65 CNR1 (0.85) CNR1CNR2
SCHEMBL3374289 0.65 CNR1 (0.85) CNR1CNR2
SCHEMBL3371918 0.65 CNR1 (0.45) CNR1CNR2
SCHEMBL3374287 0.65 CNR1 (0.78) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6972295-B2 Substituted amides MERCK & CO., INC. (US) 2005-12-06 US disclosed