SCHEMBL649147

SCHEMBL649147

O=C(OI)c1cc[nH]n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27513898 0.78
SCHEMBL28475296 0.78
SCHEMBL28696144 0.78
SCHEMBL28204045 0.78
SCHEMBL28457471 0.78
SCHEMBL877674 0.78
SCHEMBL3998685 0.78 MAPK1 (0.33)
SCHEMBL28252877 0.77
Hydrochloric Acid SCHEMBL7838091 0.77 MAPK1 (0.48)
SCHEMBL1273234 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1628962-B1 Iodopyrazolyl carboxanilides BAYER IP GMBH (DE) 2014-10-01 EP claimed
US-7906656-B2 Iodopyrazolyl carboxanilides BAYER CROPSCIENCE AG (DE) 2011-03-15 US claimed
US-20100152266-A1 Iodopyrazolyl Carboxanilides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2010-06-17 US claimed
CN-100558710-C Iodopyrazolylcarboxanilides BAYER CROPSCIENCE AG (DE) 2009-11-11 CN claimed
US-20070066673-A1 Iodopyrazolyl carboxanilides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2007-03-22 US claimed
CN-1791582-A Iodopyrazolylcarboxanilides BAYER CROPSCIENCE AG (DE) 2006-06-21 CN claimed
CN-109265400-A Arginine methyltransferase inhibitor and application thereof EPIZYME股份有限公司 2019-01-25 CN disclosed
CN-105339351-B Arginine methyltransferase inhibitors and uses thereof EPIZYME股份有限公司 2018-11-06 CN disclosed
US-8119682-B2 Iodopyrazolyl carboxanilides BAYER CROPSCIENCE AG (DE) 2012-02-21 US disclosed
US-20110124698-A1 Iodopyrazolyl Carboxanilides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2011-05-26 US disclosed
US-7906656-B2 Iodopyrazolyl carboxanilides BAYER CROPSCIENCE AG (DE) 2011-03-15 US disclosed
US-20100152266-A1 Iodopyrazolyl Carboxanilides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2010-06-17 US disclosed
US-7687531-B2 N-(3',4'dichloro-5-fluoro-1,1'-biphenyl-2-yl)-3-iodo-1-methyl-1H-pyrazole4-carboxamide; fungicides; molds/fungi/; plants/organisms/; controlling microorganisms; microbiocides; dermatophytes; Candida; Epidermophyton; Aspergillus; Trichophyton BAYER CROPSCIENCE AG (DE) 2010-03-30 US disclosed
CN-100558710-C Iodopyrazolylcarboxanilides BAYER CROPSCIENCE AG (DE) 2009-11-11 CN disclosed
US-20070066673-A1 Iodopyrazolyl carboxanilides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2007-03-22 US disclosed
CN-1791582-A Iodopyrazolylcarboxanilides BAYER CROPSCIENCE AG (DE) 2006-06-21 CN disclosed