Butylparaben

Butylparaben

SCHEMBL649214

CCCCOC(=O)c1ccc(O)cc1.CCCOC(=O)c1ccc(O)cc1

nearest known ligand 0.93

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 10/20 0.93
TSHR P16473 3/20 0.93
LMNA P02545 3/20 0.93
CYP1A2 P05177 2/20 0.93
CYP2C19 P33261 2/20 0.93
CYP2D6 P10635 1/20 0.93
MAPK1 P28482 1/20 0.93
NR1H2 P55055 1/20 0.93
RNASEL Q05823 1/20 0.93
SMN1; SMN2 Q16637 1/20 0.93
ALDH1A1 P00352 2/20 0.86
CHRM1 P11229 1/20 0.86
SLC6A2 P23975 1/20 0.86
KDR P35968 1/20 0.86
TDP1 Q9NUW8 1/20 0.86
CYP3A4 P08684 1/20 0.68
CYP2C9 P11712 1/20 0.68
PDE4D Q08499 1/20 0.68
CA12 O43570 1/20 0.62
CA1 P00915 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butylparaben SCHEMBL31393220 1.00 ESR1 (0.93) ESR1TSHRLMNACYP1A2CYP2C19
Butylparaben SCHEMBL5789201 0.96 ESR1 (1.00) ESR1TSHRLMNACYP1A2CYP2C19
Butylparaben SCHEMBL3647 0.96 ESR1 (1.00) ESR1TSHRLMNACYP1A2CYP2C19
Butylparaben SCHEMBL16862676 0.95 ESR1 (0.84) ESR1TSHRLMNACYP1A2CYP2C19
Butylparaben SCHEMBL9172319 0.95 ESR1 (0.96) ESR1TSHRLMNACYP1A2CYP2C19
Butylparaben SCHEMBL2325184 0.95 ESR1 (0.96) ESR1TSHRLMNACYP1A2CYP2C19
Butylparaben SCHEMBL761983 0.95 ESR1 (0.96) ESR1TSHRLMNACYP1A2CYP2C19
Butylparaben SCHEMBL29376702 0.95 ESR1 (0.96) ESR1TSHRLMNACYP1A2CYP2C19
Butylparaben SCHEMBL5152448 0.95 ESR1 (0.96) ESR1TSHRLMNACYP1A2CYP2C19
Butylparaben SCHEMBL29377478 0.95 ESR1 (0.96) ESR1TSHRLMNACYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7666451-B2 Method of treating dyshidrosis(pompholyx) and related dry skin disorders MAZZIO ELIZABETH ANNE 2010-02-23 US claimed
US-20090004301-A1 Method of treating dyshidrosis(pompholyx) and related dry skin disorders MAZZIO ELIZABETH 2009-01-01 US claimed
US-7357950-B2 Topical treatment for dyshidrosis (pompholyx) and dry skin disorders MAZZIO ELIZABETH ANNE 2008-04-15 US claimed
US-20040185123-A1 Topical treatment for dyshidrosis (pompholyx) and dry skin disorders MAZZIO ELIZABETH A (US) 2004-09-23 US claimed
CN-117531228-A Use of coconut water as extraction solvent 巴斯夫美容护理法国公司 2024-02-09 CN disclosed
CN-117355290-A Hair coloring composition for reducing color loss 路博润先进材料公司 2024-01-05 CN disclosed
CN-110167527-B Use of coconut water as extraction solvent 巴斯夫美容护理法国公司 2023-11-17 CN disclosed
CN-112118831-B Tabletted chewing gum sweet suitable for active pharmaceutical ingredient 费尔廷制药公司 2023-04-21 CN disclosed
EP-3781211-A1 POWDER COMPOSITION FOR COSMETIC AND HEALTH USE Speximo AB (SE) 2021-02-24 EP disclosed
WO-2019203717-A1 POWDER COMPOSITION FOR COSMETIC AND HEALTH USE SPEXIMO AB (SE) 2019-10-24 WO disclosed
EP-2421494-B1 METHOD FOR PRODUCING FREE POWDER PARTICLES OF POLYAMIDE IMPREGNATED WITH AT LEAST ONE COSMETIC OR PHARMACEUTICAL AGENT, AND FREE POWDER PARTICLES OF POLYAMIDE HAVING A CONTENT OF AT LEAST 25 WT % OF AT LEAST ONE COSMETIC OR PHARMACEUTICAL AGENT ARKEMA FRANCE (FR) 2018-02-07 EP disclosed
US-9764167-B2 Method for producing free powder particles of polyamide impregnated with at least one cosmetic or pharmaceutical agent, and free powder particles of polyamide having a content of at least 25 WT % of a cosmetic or pharmaceutical agent other than water ARKEMA FRANCE (FR) 2017-09-19 US disclosed
EP-1423448-A4 POLYMERIC URETHANE ESTER QUATS AND THEIR USE IN PERSONAL CARE COMPOSITIONS ALZO INT INC (US) 2005-06-29 EP disclosed
EP-1423448-A2 POLYMERIC URETHANE ESTER QUATS AND THEIR USE IN PERSONAL CARE COMPOSITIONS Alzo International, Inc. (US) 2004-06-02 EP disclosed
WO-2003016247-A2 POLYMERIC URETHANE ESTER QUATS AND THEIR USE IN PERSONAL CARE COMPOSITIONS ALZO INTERNATIONAL, INC. (US) 2003-02-27 WO disclosed
US-5972317-A NAIL-PERMEABLE MEDICATION MEANS IS DISCLOSED FOR DELIVERING A MEDICAMENT THROUGH NAILS, CLAWS, HOOFS, OR OTHER SIMILAR HARDENED TISSUE OF DERMAL DERIVATION; INCLUDES PROTEOLYTIC ENZYME AND DRUG SELECTED TO TREAT SPECIFIC DISEASE SORENSON PHARMACEUTICAL, INC. (US) 1999-10-26 US disclosed
EP-0866683-A4 COMPOSITION AND METHOD FOR TREATING DISEASED NAILS SORENSON PHARMACEUTICAL INC (US) 1999-01-07 EP disclosed
US-5840283-A NAIL-PERMEABLE COMPOSITION COMPRISING PROTEOLYTIC ENZYME AND DISEASE AFFECTING MEDICAMENT IN TOPICALLY SPREADABLE FORM SORENSON PHARMACEUTICAL, INC. (US) 1998-11-24 US disclosed
EP-0866683-A1 COMPOSITION AND METHOD FOR TREATING DISEASED NAILS Sorenson Pharmaceutical, Inc. (US) 1998-09-30 EP disclosed
WO-1997009960-A1 COMPOSITION AND METHOD FOR TREATING DISEASED NAILS SORENSON PHARMACEUTICAL, INC. (US) 1997-03-20 WO disclosed