Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EEF2K | O00418 | 2/20 | 0.37 |
| ▸ | EEF2 | P13639 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 6/20 | 0.36 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6498625 | 0.92 | EEF2K (0.39) | EEF2KEEF2DPP4EPHA2FLT4 | |
| SCHEMBL6498630 | 0.92 | EEF2K (0.39) | EEF2KEEF2DPP4EPHA2FLT4 | |
| SCHEMBL6490387 | 0.92 | EEF2K (0.39) | EEF2KEEF2DPP4EPHA2FLT4 | |
| SCHEMBL6497881 | 0.88 | EEF2K (0.36) | EEF2KEEF2DPP4EPHA2FLT4 | |
| SCHEMBL6495387 | 0.86 | DPP4 (0.39) | EEF2KEEF2DPP4EPHA2FLT4 | |
| SCHEMBL4515916 | 0.83 | DPP4 (0.34) | EEF2KEEF2DPP4EPHA2FLT4 | |
| SCHEMBL4515912 | 0.83 | DPP4 (0.34) | EEF2KEEF2DPP4EPHA2FLT4 | |
| SCHEMBL4515910 | 0.83 | DPP4 (0.34) | EEF2KEEF2DPP4EPHA2FLT4 | |
| SCHEMBL1385881 | 0.83 | EPHA2 (0.46) | EEF2KEEF2DPP4EPHA2FLT4 | |
| Hydrochloric Acid SCHEMBL4520597 | 0.82 | DPP4 (0.34) | EEF2KEEF2DPP4EPHA2FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050119231-A1 | Quinolone antibacterial agents | ELLSWORTH EDMUND L (US) | 2005-06-02 | — | — | US | claimed |
| US-20050119231-A1 | Quinolone antibacterial agents | ELLSWORTH EDMUND L (US) | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119231-A1 | Quinolone antibacterial agents | NQO2, MRPL21, TOP1 | EEF2K 859/4885EEF2 727/4885DPP4 1802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.