⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL27461973 | 0.92 | — | — | |
| SCHEMBL4621927 | 0.92 | FABP6 (0.35) | — | |
| SCHEMBL80643 | 0.92 | — | — | |
| SCHEMBL969300 | 0.92 | — | — | |
| SCHEMBL4198 | 0.92 | — | — | |
| Methylamine SCHEMBL27885237 | 0.90 | — | — | |
| Hydroxyamine SCHEMBL27914147 | 0.90 | — | — | |
| Iodide SCHEMBL7938108 | 0.89 | — | — | |
| SCHEMBL7117843 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL2080171 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1330647-C | Heterobicyclic substituted phenyl * oxazolidinone antibacterial agents | ORTHO MCNELL PHARMACEUTICAL IN (US) | 2007-08-08 | — | — | CN | disclosed |
| CN-1250544-C | Pyridoarylphenyl oxazolidinone antibacterial agents and related compositions and methods | ORTHO MCNEIL PHARM INC (US) | 2006-04-12 | — | — | CN | disclosed |
| US-6951863-B2 | Pyridoarylphenly oxazolidinone antibacterials, and related compositions and methods | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2005-10-04 | — | — | US | disclosed |
| CN-1642949-A | Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterial, related compositions and methods | ORTHO MCNEIL PHARM INC (US) | 2005-07-20 | — | — | CN | disclosed |
| EP-1470123-A1 | BICYCLIC HETEROCYCLIC SUBSTITUTED PHENYL OXAZOLIDINONE ANTIBACTERIALS, RELATED COMPOSITIONS AND METHODS | Ortho-Mcneil Pharmaceutical, Inc. (US) | 2004-10-27 | — | — | EP | disclosed |
| US-6770664-B2 | PYRROLO(3,4-C)PYRAZOL-5(4H)-YL)-3-FLUOROPHENYL)-2-OXO-5 -OXAZOLIDINYL)METHYL)ACETAMIDE DERIVATIVES; BACTERICIDES AGAINST DRUG RESISTANT STAPHYLOCOCCUS, STREPTOCOCCUS, AND/OR ENTEROCOCCUS | PAGET STEVEN D (US) | 2004-08-03 | — | — | US | disclosed |
| US-20040067994-A1 | BICYCLIC HETEROCYCLIC SUBSTITUTED PHENYL OXAZOLIDINONE ANTIBACTERIALS, AND RELATED COMPOSITIONS AND METHODS | PAGET STEVEN D (US) | 2004-04-08 | — | — | US | disclosed |
| EP-1206469-B1 | ANTIBACTERIAL HETEROBICYCLIC SUBSTITUTED PHENYL OXAZOLIDINONES | ORTHO MCNEIL PHARM INC (US) | 2004-02-25 | — | — | EP | disclosed |
| CN-1460104-A | Pyridoarylphenyl oxazolidinone antibacterials and related compositions and methods | ORTHO MCNEIL PHARM INC (US) | 2003-12-03 | — | — | CN | disclosed |
| EP-1358185-A2 | PYRIDOARYLPHENYL OXAZOLIDINONE ANTIBACTERIALS, AND RELATED COMPOSITIONS AND METHODS | Ortho-Mcneil Pharmaceutical, Inc. (US) | 2003-11-05 | — | — | EP | disclosed |
| US-20030176422-A1 | For therapy of bacterial infections in humans and animals | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2003-09-18 | — | — | US | disclosed |
| US-20030171366-A1 | Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods | PAGET STEVEN (US) | 2003-09-11 | — | — | US | disclosed |
| US-6608081-B2 | Treating pneumonia | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2003-08-19 | — | — | US | disclosed |
| WO-2003064415-A1 | BICYCLIC HETEROCYCLIC SUBSTITUTED PHENYL OXAZOLIDINONE ANTIBACTERIAL, RELATED COMPOSITIONS AND METHODS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2003-08-07 | — | — | WO | disclosed |
| CN-1414964-A | heterobicyclic substituted phenyl oxazolidinone antibacterial agents | ORTHO MCNELL PHARMACEUTICAL IN (US) | 2003-04-30 | — | — | CN | disclosed |
| US-20020161029-A1 | Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2002-10-31 | — | — | US | disclosed |
| WO-2002064574-A2 | PYRIDOARYLPHENYL OXAZOLIDINONE ANTIBACTERIALS, AND RELATED COMPOSITIONS AND METHODS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2002-08-22 | — | — | WO | disclosed |
| US-6413981-B1 | DRUG-RESISTANT GRAM POSITIVE AND GRAM NEGATIVE BACTERIA; PNEUMONIA; INFECTIONS OF UPPER AND LOWER RESPIRATORY TRACT, SKIN, SOFT TISSUE, BONES AND JOINTS | ORTHO-MCNEIL PHARAMCEUTICAL, INC. | 2002-07-02 | — | — | US | disclosed |
| EP-1206469-A1 | ANTIBACTERIAL HETEROBICYCLIC SUBSTITUTED PHENYL OXAZOLIDINONES | Ortho-McNeil Pharmaceutical, Inc. (US) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001042242-A1 | ANTIBACTERIAL HETEROBICYCLIC SUBSTITUTED PHENYL OXAZOLIDINONES | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-06-14 | — | — | WO | disclosed |