SCHEMBL649312

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL649314	1.00	HPGD (0.43)	HPGDKDRALOX5MEN1KMT2A
	SCHEMBL650961	0.87	MAPT (0.38)	HPGDMEN1KMT2AMAPTNPSR1
	SCHEMBL650959	0.87	MAPT (0.38)	HPGDMEN1KMT2AMAPTNPSR1
	SCHEMBL651184	0.83	MAPT (0.38)	HPGDMEN1KMT2ANPC1MAPT
	SCHEMBL651186	0.83	MAPT (0.38)	HPGDMEN1KMT2ANPC1MAPT
	SCHEMBL10176552	0.83	HPGD (0.47)	HPGDKDRALOX5MEN1KMT2A
	SCHEMBL649313	0.83	HPGD (0.47)	HPGDKDRALOX5MEN1KMT2A
	SCHEMBL649545	0.82	HPGD (0.44)	HPGDKDRALOX5MEN1KMT2A
	SCHEMBL10176445	0.82	HPGD (0.44)	HPGDKDRALOX5MEN1KMT2A
	SCHEMBL652913	0.81	HPGD (0.46)	HPGDKDRALOX5MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.