Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 17/20 | 0.62 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.61 |
| ▸ | PPARA | Q07869 | 11/20 | 0.56 |
| ▸ | PPARG | P37231 | 9/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6487449 | 0.93 | PPARD (0.62) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL6487765 | 0.91 | FFAR1 (0.53) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL6491580 | 0.91 | PPARD (0.60) | PPARDFFAR1PPARAPPARGMCL1 | |
| SCHEMBL6487960 | 0.87 | PPARA (0.65) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL5017503 | 0.86 | PPARD (0.65) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL6497348 | 0.84 | FFAR1 (0.53) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL5017471 | 0.84 | PPARD (0.56) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL6494057 | 0.84 | PPARD (0.60) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL5015470 | 0.84 | PPARD (0.55) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL6486158 | 0.83 | PPARD (0.53) | PPARDFFAR1PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050203151-A1 | Novel compounds, compositions and uses thereof for treatment of metabolic disorders and related conditions | KALYPSYS, INC. (US) | 2005-09-15 | — | — | US | disclosed |
| WO-2005060958-A1 | (5- (2-PHENYL)-THIAZOL-5-YLMETHOXY)-INDOL-1-YL) -ACETIC ACID DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS OF THE HUMAN PPAR-DELTA RECEPTOR FOR THE TREATMENT OF METABOLIC DISORDERS SUCH AS TYPE 2 DIABETES | KALYPSYS, INC. (US) | 2005-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203151-A1 | Novel compounds, compositions and uses thereof for treatment of metabolic disorders and related conditions | PPARG, PPARD, PPARA | PPARD 2/4885FFAR1 43/4885PPARA 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.