Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 9/20 | 0.69 |
| ▸ | HTR1B | P28222 | 8/20 | 0.69 |
| ▸ | HTR2A | P28223 | 4/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6488819 | 0.93 | HTR1D (0.69) | HTR1DHTR1BHTR2ACYP3A4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6486379 | 0.91 | HTR1D (0.69) | HTR1DHTR1BHTR2ACYP3A4ALDH1A1 | |
| SCHEMBL6497266 | 0.90 | HTR1D (0.68) | HTR1DHTR1BHTR2ACYP3A4ALDH1A1 | |
| SCHEMBL6531432 | 0.89 | HTR1D (0.65) | HTR1DHTR1BHTR2ACYP3A4ALDH1A1 | |
| SCHEMBL6502023 | 0.89 | HTR1D (0.65) | HTR1DHTR1BHTR2ACYP3A4ALDH1A1 | |
| SCHEMBL6498021 | 0.89 | HTR1D (0.81) | HTR1DHTR1BHTR2ACYP3A4ALDH1A1 | |
| SCHEMBL6495150 | 0.89 | HTR1D (0.68) | HTR1DHTR1BHTR2ACYP3A4ALDH1A1 | |
| SCHEMBL6498634 | 0.88 | HTR1D (0.66) | HTR1DHTR1BHTR2ACYP3A4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6494904 | 0.88 | HTR1D (0.67) | HTR1DHTR1BHTR2ACYP3A4ALDH1A1 | |
| SCHEMBL6489358 | 0.88 | HTR1D (0.65) | HTR1DHTR1BHTR2ACYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050065195-A1 | Oxadiazolyl-biphenylcarboxamides and their use as p38 kinase inhibitors | GLAXO GROUP LIMITED (GB) | 2005-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065195-A1 | Oxadiazolyl-biphenylcarboxamides and their use as p38 kinase inhibitors | MAPK3, MAPK1, MAPKAPK3 | HTR1D 1697/4885HTR1B 1495/4885HTR2A 2476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.