Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16104359 | 0.94 | DDB1 (0.54) | DDB1CRBNOPRM1TACR1ALDH1A1 | |
| SCHEMBL1200111 | 0.89 | DDB1 (0.54) | DDB1CRBNALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL3555789 | 0.86 | DDB1 (0.51) | DDB1CRBNALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL595870 | 0.86 | DDB1 (0.51) | DDB1CRBNALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL4429190 | 0.84 | DDB1 (0.50) | DDB1CRBNALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL13311996 | 0.83 | DDB1 (0.56) | DDB1CRBNOPRM1TACR1ALDH1A1 | |
| SCHEMBL26130614 | 0.83 | DDB1 (0.52) | DDB1CRBNOPRM1TACR1ALDH1A1 | |
| SCHEMBL8143637 | 0.83 | DDB1 (0.47) | DDB1CRBNALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL16661304 | 0.82 | DDB1 (0.56) | DDB1CRBNALDH1A1MAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL3497895 | 0.82 | DDB1 (0.55) | DDB1CRBNOPRM1TACR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170850-B1 | NOVEL DICARBOXYLIC ACID DERIVATIVES AS S1P1 RECEPTOR AGONISTS | BIOPROJET SOC CIV (FR) | 2014-09-24 | — | — | EP | disclosed |
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |
| EP-1326619-A2 | PYRROLIDINE MODULATORS OF CCR5 CHEMOKINE RECEPTOR ACTIVITY | Merck & Co., Inc. (US) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002034716-A2 | PYRROLIDINE MODULATORS OF CCR5 CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO., INC. (US) | 2002-05-02 | — | — | WO | disclosed |