Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 18/20 | 0.79 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.79 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.79 |
| ▸ | PDE2A | O00408 | 1/20 | 0.79 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.79 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.79 |
| ▸ | PDE6D | O43924 | 1/20 | 0.79 |
| ▸ | PDE8A | O60658 | 1/20 | 0.79 |
| ▸ | PDE9A | O76083 | 1/20 | 0.79 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.79 |
| ▸ | HTR1A | P08908 | 1/20 | 0.79 |
| ▸ | PDE6A | P16499 | 1/20 | 0.79 |
| ▸ | PDE6G | P18545 | 1/20 | 0.79 |
| ▸ | PDE4A | P27815 | 1/20 | 0.79 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.79 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.79 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.79 |
| ▸ | PDE6B | P35913 | 1/20 | 0.79 |
| ▸ | PDE6C | P51160 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25925162 | 1.00 | PDE5A (0.79) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL6497382 | 1.00 | PDE5A (0.79) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL30434848 | 1.00 | PDE5A (0.79) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL29394704 | 1.00 | PDE5A (0.79) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL28891471 | 0.95 | PDE5A (0.73) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL14929265 | 0.92 | PDE5A (0.79) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL5450733 | 0.92 | PDE5A (0.66) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL5450729 | 0.92 | PDE5A (0.66) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL5450646 | 0.92 | PDE5A (0.66) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL5450606 | 0.92 | PDE5A (0.66) | PDE5APDE3BPDE3APDE2AABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113350301-B | New compound traditional Chinese medicine honeyed pill for treating impotence | 刘宝顺 | 2022-10-04 | — | — | CN | claimed |
| CN-113350301-A | New compound traditional Chinese medicine honeyed pill for treating impotence | 刘宝顺 | 2021-09-07 | — | — | CN | claimed |
| CN-111297868-A | Use of a composition comprising a heterocyclic compound for the manufacture of a medicament for the treatment of phosphodiesterase mediated diseases | 黄泳华 | 2020-06-19 | — | — | CN | claimed |
| EP-1400522-B1 | COMPOUNDS FOR TREATING IMPOTENCE | GUANGZHOU YOUCARE BIOPHARMACEATICS CO LTD (CN) | 2014-08-06 | — | — | EP | claimed |
| US-6960592-B2 | 1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one compound for the treatment of impotence | LIU BAOSHUN | 2005-11-01 | — | — | US | claimed |
| US-20040152709-A1 | New compound for the treatment of impotence | LIU BAOSHUN (CN) | 2004-08-05 | — | — | US | claimed |
| EP-1400522-A1 | NEW COMPOUNDS FOR TREATING IMPOTENCE | Liu, Baoshun (CN) | 2004-03-24 | — | — | EP | claimed |
| CN-119367314-A | Aidinafil sustained-release pellet and preparation method and application thereof | 北京悦康科创医药科技股份有限公司 | 2025-01-28 | — | — | CN | disclosed |
| CN-116262118-B | Application of alidenafil or salt thereof in preparation of medicines for preventing or treating ischemic brain injury | 真奥金银花药业有限公司 | 2024-03-29 | — | — | CN | disclosed |
| WO-2023109513-A1 | USE OF AILDENAFIL OR SALT THEREOF IN PREPARATION OF MEDICINE FOR PREVENTING OR TREATING ISCHEMIC BRAIN DAMAGE | 真奥金银花药业有限公司 | 2023-06-22 | — | — | WO | disclosed |
| CN-116262118-A | Application of alidenafil or salt thereof in preparation of medicines for preventing or treating ischemic brain injury | 真奥金银花药业有限公司 | 2023-06-16 | — | — | CN | disclosed |
| CN-113350301-B | New compound traditional Chinese medicine honeyed pill for treating impotence | 刘宝顺 | 2022-10-04 | — | — | CN | disclosed |
| CN-115054520-A | Preparation process of traditional Chinese medicine honeyed pill for treating impotence | 刘宝顺 | 2022-09-16 | — | — | CN | disclosed |
| WO-2017133517-A1 | PHOSPHAMIDE DERIVATIVE, METHOD FOR MANUFACTURING THE SAME, AND USES THEREOF | 四川海思科制药有限公司 | 2017-08-10 | — | — | WO | disclosed |
| US-9663439-B2 | Aildenafil citrate crystal form O, preparation method and use thereof | HONG KONG GOLDEN WISDOM MEDICAL PRODUCTION LIMITED (HK) | 2017-05-30 | — | — | US | disclosed |
| EP-1400522-B1 | COMPOUNDS FOR TREATING IMPOTENCE | GUANGZHOU YOUCARE BIOPHARMACEATICS CO LTD (CN) | 2014-08-06 | — | — | EP | disclosed |
| US-20130165448-A1 | AILDENAFIL CITRATE CRYSTAL FORM O, PREPARATION METHOD AND USE THEREOF | HONG KONG GOLDEN WISDOM MEDICAL PRODUCTION LIMITED (HK) | 2013-06-27 | — | — | US | disclosed |
| US-6960592-B2 | 1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one compound for the treatment of impotence | LIU BAOSHUN | 2005-11-01 | — | — | US | disclosed |
| US-20040152709-A1 | New compound for the treatment of impotence | LIU BAOSHUN (CN) | 2004-08-05 | — | — | US | disclosed |
| EP-1400522-A1 | NEW COMPOUNDS FOR TREATING IMPOTENCE | Liu, Baoshun (CN) | 2004-03-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165448-A1 | AILDENAFIL CITRATE CRYSTAL FORM O, PREPARATION METHOD AND USE THEREOF | PDE5A, PDE3A, PDE3B | PDE5A 1/4885PDE3B 3/4885PDE3A 2/4885 |
| US-20040152709-A1 | New compound for the treatment of impotence | PDE3B, PDE3A, PDE5A | PDE5A 3/4885PDE3B 1/4885PDE3A 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.