⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL127729 | 0.92 | — | — | |
| SCHEMBL198404 | 0.89 | TSHR (0.46) | — | |
| SCHEMBL199607 | 0.89 | TSHR (0.46) | — | |
| SCHEMBL198402 | 0.89 | TSHR (0.46) | — | |
| SCHEMBL200927 | 0.89 | TSHR (0.46) | — | |
| SCHEMBL200017 | 0.89 | TSHR (0.46) | — | |
| SCHEMBL200125 | 0.89 | TSHR (0.46) | — | |
| SCHEMBL817536 | 0.89 | TSHR (0.46) | — | |
| SCHEMBL817293 | 0.89 | TSHR (0.46) | — | |
| SCHEMBL198896 | 0.89 | TSHR (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1546 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110191885-B | Alkoxy bis-heteroaryl derivatives as modulators of protein aggregation | UCB生物制药私人有限公司 | 2023-05-16 | — | — | CN | claimed |
| US-11548900-B2 | Oxazino-quinazoline and oxazino-quinoline type compound, preparation method and uses thereof | BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED (CN) | 2023-01-10 | — | — | US | claimed |
| CN-114479645-B | Preparation method of polyurethane waterproof coating | 江苏凯伦建材股份有限公司 | 2022-11-11 | — | — | CN | claimed |
| WO-2022160584-A1 | POLYURETHANE WATERPROOF COATING, PREPARATION METHOD THEREFOR AND USE THEREOF | 江苏凯伦建材股份有限公司 | 2022-08-04 | — | — | WO | claimed |
| CN-114479645-A | Preparation method of polyurethane waterproof coating | 江苏凯伦建材股份有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-112898889-B | Polyurethane waterproof coating and application thereof | 江苏凯伦建材股份有限公司 | 2022-04-01 | — | — | CN | claimed |
| EP-3760633-B1 | OXAZINO-QUINAZOLINE AND OXAZINO-QUINAZOLINE TYPE COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF | BEIJING SCITECH MQ PHARMACEUTICALS LTD (CN) | 2021-12-15 | — | — | EP | claimed |
| US-11091474-B2 | Alkoxy bis-heteroaryl derivatives as modulators of protein aggregation | UCB Biopharma SRL (BE) | 2021-08-17 | — | — | US | claimed |
| CN-112898889-A | Polyurethane waterproof coating and application thereof | 江苏凯伦建材股份有限公司 | 2021-06-04 | — | — | CN | claimed |
| CN-110229171-B | Oxazinoquinazoline and oxazinoquinoline compound and preparation method and application thereof | 北京赛特明强医药科技有限公司 | 2021-03-12 | — | — | CN | claimed |
| US-6207763-B1 | A COPOLYMER OF SUBSTITUTED OR UNSUBSTITUTED 1-20 ALKYL GROUP DISUBSTITUTED ETHYLENE-MALEIMIDE COPOLYMER(A REACTION PRODUCT OF DISUBTITUTED ETHYLENE-MALEIC ANHYDRIDE IMIDIZED WITH PRIMARY AMINE) IS A PLASTICIZER FOR RUBBER; HIGH DAMPING | BRIDGESTONE CORPORATION (JP) | 2001-03-27 | — | — | US | claimed |
| US-6191217-B1 | REACTING POLY(ALKYL VINYLETHER-CO-MALEIMIDE) POLYMER WITH MALEATED POLYALKYLENE AND ALKYL DIAMINE UNDER SUBSTANTIALLY DRY CONDITIONS SUFFICIENT TO FORM POLYALKYLENE GRAFTED POLY(ALKYL VINYLETHER-CO-MALEIMIDE) POLYMER | BRIDGESTONE CORPORATION (JP) | 2001-02-20 | — | — | US | claimed |
| US-6133354-A | MIXING A POLY(DIALKYLSUBSTITUTED ETHYLENE-CO-MALEIMIDE) POLYMER SUCH AS POLYISOBUTYLENE-CO-MALEIMIDE, AND PLASTICIZERS OR EXTENDERS WITHIN A NON-VULCANIZED THERMOPLASTIC ELASTOMER TO FORM A DAMPING GEL; TENSILE STRENGTH AND TEAR STRENGTH | BRIDGESTONE CORPORATION (JP) | 2000-10-17 | — | — | US | claimed |
| EP-0955319-A1 | Soft compounds derived from polypropylene grafted disubstituted ethylene-maleimide copolymers | Bridgestone Corporation (JP) | 1999-11-10 | — | — | EP | claimed |
| EP-0422178-B1 | PYRIMIDINE DERIVATIVES | ZENECA LTD (GB) | 1994-10-05 | — | — | EP | claimed |
| US-5223505-A | PYRIMIDINE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-06-29 | — | — | US | claimed |
| US-5106892-A | Containing synergistic mixture of organic phosphites | AUSIMONT S.P.A. (IT) | 1992-04-21 | — | — | US | claimed |
| EP-0422178-A1 | PYRIMIDINE DERIVATIVES. | ICI PLC (GB) | 1991-04-17 | — | — | EP | claimed |
| US-5008452-A | Antidepressants, sedatives and anticonvulsants | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1991-04-16 | — | — | US | claimed |
| WO-1990012790-A1 | PYRIMIDINE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-11-01 | — | — | WO | claimed |