Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 8/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | CCR8 | P51685 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6498402 | 1.00 | SLC2A1 (0.60) | SLC2A1KCNH2CCR8CYP2D6KDM4E | |
| SCHEMBL6648662 | 1.00 | SLC2A1 (0.60) | SLC2A1KCNH2CCR8CYP2D6KDM4E | |
| SCHEMBL6497372 | 1.00 | SLC2A1 (0.60) | SLC2A1KCNH2CCR8CYP2D6KDM4E | |
| SCHEMBL6645390 | 1.00 | SLC2A1 (0.60) | SLC2A1KCNH2CCR8CYP2D6KDM4E | |
| SCHEMBL6498397 | 1.00 | SLC2A1 (0.60) | SLC2A1KCNH2CCR8CYP2D6KDM4E | |
| SCHEMBL6645394 | 1.00 | SLC2A1 (0.60) | SLC2A1KCNH2CCR8CYP2D6KDM4E | |
| SCHEMBL6648669 | 1.00 | SLC2A1 (0.60) | SLC2A1KCNH2CCR8CYP2D6KDM4E | |
| SCHEMBL6645387 | 1.00 | SLC2A1 (0.60) | SLC2A1KCNH2CCR8CYP2D6KDM4E | |
| Oxalic Acid SCHEMBL6484821 | 0.95 | SLC2A1 (0.60) | SLC2A1KCNH2CCR8 | |
| Oxalic Acid SCHEMBL6484327 | 0.95 | SLC2A1 (0.60) | SLC2A1KCNH2CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187828-B1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2004-04-21 | — | — | EP | claimed |
| US-6911442-B1 | Quinoline derivatives as antibacterials | SMITHKLINE BEECHAM P.L.C. (GB) | 2005-06-28 | — | — | US | disclosed |
| EP-1187828-B1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2004-04-21 | — | — | EP | disclosed |
| EP-1187828-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2002-03-20 | — | — | EP | disclosed |
| WO-2000078748-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-12-28 | — | — | WO | disclosed |