Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6490336 | 0.93 | KCNH2 (0.52) | KCNH2TOP1 | |
| SCHEMBL1384477 | 0.90 | KCNH2 (0.59) | KCNH2TOP1 | |
| SCHEMBL14160482 | 0.90 | KCNH2 (0.51) | KCNH2TOP1 | |
| SCHEMBL6492803 | 0.90 | KCNH2 (0.51) | KCNH2TOP1 | |
| Hydrochloric Acid SCHEMBL4517172 | 0.89 | KCNH2 (0.59) | KCNH2TOP1 | |
| SCHEMBL14444912 | 0.87 | KCNH2 (0.48) | KCNH2TOP1 | |
| SCHEMBL1384056 | 0.86 | KCNH2 (0.52) | KCNH2TOP1 | |
| SCHEMBL6372385 | 0.86 | KCNH2 (0.45) | KCNH2TOP1 | |
| SCHEMBL1385092 | 0.85 | KCNH2 (0.47) | KCNH2TOP1 | |
| Hydrochloric Acid SCHEMBL4517768 | 0.85 | KCNH2 (0.51) | KCNH2TOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050119231-A1 | Quinolone antibacterial agents | ELLSWORTH EDMUND L (US) | 2005-06-02 | — | — | US | claimed |
| US-20050119231-A1 | Quinolone antibacterial agents | ELLSWORTH EDMUND L (US) | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119231-A1 | Quinolone antibacterial agents | NQO2, MRPL21, TOP1 | KCNH2 2108/4885TOP1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.