Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 9/20 | 0.41 |
| ▸ | HTR2B | P41595 | 6/20 | 0.41 |
| ▸ | HTR2A | P28223 | 6/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6499878 | 1.00 | HTR2C (0.41) | HTR2CHTR2BHTR2APIK3CDPIK3C2B | |
| SCHEMBL6783931 | 0.92 | HTR2C (0.42) | HTR2CHTR2BHTR2APIK3CDPIK3C2B | |
| SCHEMBL6785120 | 0.86 | HTR2C (0.40) | HTR2CHTR2BHTR2A | |
| SCHEMBL6783840 | 0.86 | HTR2C (0.43) | HTR2CHTR2BHTR2A | |
| SCHEMBL6505194 | 0.85 | CNR2 (0.34) | HTR2CHTR2BHTR2AEGFRCNR2 | |
| SCHEMBL6782654 | 0.85 | HTR2C (0.42) | HTR2CHTR2BHTR2ACNR2 | |
| SCHEMBL6503694 | 0.84 | HTR2C (0.38) | HTR2CHTR2BHTR2AEPHX2 | |
| SCHEMBL6490201 | 0.84 | IDH2 (0.41) | HTR2CHTR2BHTR2A | |
| SCHEMBL6492420 | 0.83 | HTR2C (0.46) | HTR2CHTR2BHTR2A | |
| SCHEMBL6502381 | 0.83 | CNR2 (0.35) | HTR2BEGFRCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6849619-B2 | Substituted pyridoindoles as serotonin agonists and antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-02-01 | — | — | US | disclosed |