Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 6/20 | 0.80 |
| ▸ | HTR1B | P28222 | 6/20 | 0.80 |
| ▸ | HTR1A | P08908 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.52 |
| ▸ | PLAU | P00749 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PLAT | P00750 | 2/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6502864 | 0.92 | HTR1D (0.70) | HTR1DHTR1BHTR1AMAPTCYP3A4 | |
| SCHEMBL6487377 | 0.91 | HTR1D (0.81) | HTR1DHTR1BHTR1AMAPTCYP3A4 | |
| SCHEMBL6488685 | 0.91 | HTR1D (0.81) | HTR1DHTR1BHTR1AMAPTCYP3A4 | |
| SCHEMBL6498021 | 0.91 | HTR1D (0.81) | HTR1DHTR1BHTR1AMAPTCYP3A4 | |
| SCHEMBL6498408 | 0.91 | HTR1D (0.81) | HTR1DHTR1BHTR1AMAPTCYP3A4 | |
| SCHEMBL6488427 | 0.91 | HTR1D (0.81) | HTR1DHTR1BHTR1AMAPTCYP3A4 | |
| SCHEMBL6488322 | 0.91 | HTR1D (0.81) | HTR1DHTR1BHTR1AMAPTCYP3A4 | |
| SCHEMBL6488282 | 0.90 | HTR1D (0.66) | HTR1DHTR1BHTR1AMAPTCYP3A4 | |
| SCHEMBL6490991 | 0.90 | HTR1D (0.80) | HTR1DHTR1BHTR1AMAPTCYP3A4 | |
| SCHEMBL6489170 | 0.89 | HTR1D (0.78) | HTR1DHTR1BHTR1AMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050065195-A1 | Oxadiazolyl-biphenylcarboxamides and their use as p38 kinase inhibitors | GLAXO GROUP LIMITED (GB) | 2005-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065195-A1 | Oxadiazolyl-biphenylcarboxamides and their use as p38 kinase inhibitors | MAPK3, MAPK1, MAPKAPK3 | HTR1D 1697/4885HTR1B 1495/4885HTR1A 2700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.