SCHEMBL650124

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL650125	1.00	KMT2A (0.42)	KMT2AMAPTMEN1MAPK1PKM
	SCHEMBL10176363	0.93	MAPT (0.41)	KMT2AMAPTMEN1MAPK1PKM
	SCHEMBL650930	0.92	MAPT (0.48)	KMT2AMAPTMEN1MAPK1PKM
	SCHEMBL650929	0.92	MAPT (0.48)	KMT2AMAPTMEN1MAPK1PKM
	SCHEMBL648672	0.85	CDC25A (0.43)	KMT2AMAPTMEN1MAPK1PKM
	SCHEMBL649998	0.85	CDC25A (0.43)	KMT2AMAPTMEN1MAPK1PKM
	SCHEMBL653415	0.85	MAPT (0.50)	KMT2AMAPTMEN1MAPK1PKM
	SCHEMBL10226368	0.85	MAPT (0.50)	KMT2AMAPTMEN1MAPK1PKM
	SCHEMBL10227773	0.85	MAPT (0.42)	KMT2AMAPTMEN1MAPK1NPSR1
	SCHEMBL10227586	0.85	MAPT (0.41)	KMT2AMAPTMEN1MAPK1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.