Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.51 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14267871 | 0.89 | MEN1 (0.54) | MEN1KMT2AADORA1ADORA2AADORA3 | |
| SCHEMBL4499576 | 0.83 | MEN1 (0.65) | MEN1KMT2AADORA1ADORA2AADORA3 | |
| SCHEMBL29126620 | 0.83 | MEN1 (0.49) | MEN1KMT2AADORA1ADORA2AADORA3 | |
| SCHEMBL28342127 | 0.82 | MEN1 (0.62) | MEN1KMT2AADORA1ADORA2AADORA3 | |
| SCHEMBL30938002 | 0.80 | ADORA1 (0.61) | MEN1KMT2AADORA1ADORA2AADORA3 | |
| SCHEMBL4150980 | 0.80 | MEN1 (0.49) | MEN1KMT2AADORA1ADORA2AMAP2K3 | |
| SCHEMBL3183738 | 0.79 | MAPK8 (0.55) | MEN1KMT2AADORA2AMAP2K3KDM4E | |
| SCHEMBL13171353 | 0.79 | MEN1 (1.00) | MEN1KMT2AADORA1ADORA2AADORA3 | |
| SCHEMBL29416730 | 0.78 | MEN1 (0.59) | MEN1KMT2AADORA1ADORA2AADORA3 | |
| SCHEMBL28815668 | 0.78 | MEN1 (0.59) | MEN1KMT2AADORA1ADORA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033085-A1 | PYRIMIDINES DERIVATIVES AS ADENOSINE RECEPTORS LIGANDS | UNIVERSITEIT LEIDEN (NL) | 2005-04-14 | — | — | WO | claimed |
| WO-2005033085-A1 | PYRIMIDINES DERIVATIVES AS ADENOSINE RECEPTORS LIGANDS | UNIVERSITEIT LEIDEN (NL) | 2005-04-14 | — | — | WO | disclosed |