Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CLK2 | P49760 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 5/20 | 0.45 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6508275 | 0.94 | KCNH2 (0.72) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL6508139 | 0.91 | KCNH2 (0.60) | KCNH2ALDH1A1POLBOPRM1KDM4E | |
| SCHEMBL6502365 | 0.86 | KCNH2 (0.64) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL6528606 | 0.84 | KCNH2 (0.60) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL6528103 | 0.84 | KCNH2 (0.75) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL6508315 | 0.83 | KCNH2 (0.80) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL6505851 | 0.83 | KCNH2 (0.66) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL6529048 | 0.82 | KCNH2 (0.66) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL6529669 | 0.81 | KCNH2 (0.67) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL6528115 | 0.81 | KCNH2 (0.71) | KCNH2ALDH1A1POLBOPRM1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049602-A1 | QUINOLONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-02 | — | — | WO | claimed |
| WO-2005049602-A1 | QUINOLONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-02 | — | — | WO | disclosed |
| WO-2005035497-A1 | CASPASE INHIBITOR COMPRISING 2-ALKYL-4-OXOBUTANOYL GROUP AND PHARMACEUTICAL COMPOSITION THEREOF | LG LIFE SCIENCES LTD. (KR) | 2005-04-21 | — | — | WO | disclosed |