Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6376661 | 0.94 | KCNH2 (0.47) | KCNH2POLBKDM4EPRKD3ALDH1A1 | |
| SCHEMBL5463875 | 0.92 | KCNH2 (0.49) | KCNH2POLBKDM4EPRKD3ALDH1A1 | |
| SCHEMBL6491029 | 0.91 | KCNH2 (0.49) | KCNH2POLBKDM4EPRKD3ALDH1A1 | |
| SCHEMBL14432209 | 0.91 | KCNH2 (0.60) | KCNH2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5458141 | 0.91 | KCNH2 (0.60) | KCNH2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4715900 | 0.91 | KCNH2 (0.60) | KCNH2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4509664 | 0.91 | KCNH2 (0.60) | KCNH2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4509668 | 0.91 | KCNH2 (0.60) | KCNH2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4513354 | 0.91 | KCNH2 (0.60) | KCNH2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4513351 | 0.91 | KCNH2 (0.60) | KCNH2CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050119231-A1 | Quinolone antibacterial agents | ELLSWORTH EDMUND L (US) | 2005-06-02 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119231-A1 | Quinolone antibacterial agents | NQO2, MRPL21, TOP1 | KCNH2 2108/4885POLB 303/4885KDM4E 4453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.