Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 20/20 | 0.80 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.66 |
| ▸ | AVPR2 | P30518 | 5/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5102063 | 0.87 | AVPR1A (0.80) | AVPR1AKCNH2AVPR2 | |
| SCHEMBL5108564 | 0.86 | AVPR1A (0.69) | AVPR1AKCNH2AVPR2 | |
| SCHEMBL14032694 | 0.86 | AVPR1A (0.68) | AVPR1AKCNH2AVPR2 | |
| SCHEMBL5108300 | 0.84 | AVPR1A (0.80) | AVPR1AKCNH2AVPR2 | |
| SCHEMBL5107939 | 0.84 | AVPR1A (0.81) | AVPR1AKCNH2AVPR2 | |
| SCHEMBL20727500 | 0.83 | AVPR1A (0.66) | AVPR1AKCNH2AVPR2 | |
| SCHEMBL24061755 | 0.81 | AVPR1A (0.61) | AVPR1AKCNH2AVPR2 | |
| SCHEMBL5107908 | 0.81 | AVPR2 (0.66) | AVPR1AKCNH2AVPR2 | |
| SCHEMBL5107852 | 0.81 | AVPR1A (0.82) | AVPR1AKCNH2AVPR2 | |
| SCHEMBL5098210 | 0.81 | AVPR1A (0.83) | AVPR1AKCNH2AVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005039565-A1 | COMBINATIONS OF COX AND VASOPRESSIN INHIBITORS FOR THE TREATMENT OF DISMENORRHEA | PFIZER LIMITED (GB) | 2005-05-06 | — | — | WO | claimed |
| WO-2005039565-A1 | COMBINATIONS OF COX AND VASOPRESSIN INHIBITORS FOR THE TREATMENT OF DISMENORRHEA | PFIZER LIMITED (GB) | 2005-05-06 | — | — | WO | disclosed |