SCHEMBL6502137

SCHEMBL6502137

CCC(C(=O)O)N(Cc1ccccc1)Cc1cccc(OCC2CN(c3ccccc3)C(=O)O2)c1

nearest known ligand 0.71

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 19/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2823952 0.84 GRM2 (1.00) GRM2
SCHEMBL2823790 0.80 GRM2 (0.84) GRM2
SCHEMBL2824718 0.76 GRM2 (1.00) GRM2
SCHEMBL2827163 0.76 GRM2 (1.00) GRM2
SCHEMBL2823723 0.75 GRM2 (0.72) GRM2
SCHEMBL2830693 0.75 GRM2 (0.74) GRM2
SCHEMBL2824453 0.75 GRM2 (0.72) GRM2
SCHEMBL2823305 0.75 GRM2 (1.00) GRM2
SCHEMBL2824241 0.75 GRM2 (0.71) GRM2
SCHEMBL2823858 0.74 GRM2 (0.79) GRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005049589-A2 HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA, DIABETES, OBESITY AND SIMILAR DISEASES CADILA HEALTHCARE LIMITED (IN) 2005-06-02 WO claimed
WO-2005049589-A2 HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA, DIABETES, OBESITY AND SIMILAR DISEASES CADILA HEALTHCARE LIMITED (IN) 2005-06-02 WO disclosed