Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1417841 | 1.00 | EGFR (0.60) | EGFRERBB2 | |
| SCHEMBL6505388 | 0.96 | EGFR (0.58) | EGFRERBB2 | |
| SCHEMBL6505387 | 0.96 | EGFR (0.58) | EGFRERBB2 | |
| SCHEMBL1417848 | 0.95 | EGFR (0.59) | EGFRERBB2 | |
| SCHEMBL1417850 | 0.95 | EGFR (0.59) | EGFRERBB2 | |
| SCHEMBL1417899 | 0.94 | EGFR (0.63) | EGFRERBB2 | |
| SCHEMBL1417896 | 0.94 | EGFR (0.63) | EGFRERBB2 | |
| SCHEMBL1418619 | 0.91 | EGFR (0.57) | EGFRERBB2 | |
| SCHEMBL1418621 | 0.91 | EGFR (0.57) | EGFRERBB2 | |
| SCHEMBL1417878 | 0.90 | EGFR (0.58) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6972288-B1 | 4-amino-quinazoline and quinoline derivatives having an inhibitory effect on signal transduction mediated by tyrosine kinases | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2005-12-06 | — | — | US | disclosed |