Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.55 |
| ▸ | PPARA | Q07869 | 17/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6502470 | 1.00 | PPARG (0.55) | PPARGPPARAESR1SLC7A5LDHA | |
| SCHEMBL6508246 | 0.92 | PPARG (0.57) | PPARGPPARASLC7A5LDHA | |
| SCHEMBL6508244 | 0.92 | PPARG (0.57) | PPARGPPARASLC7A5LDHA | |
| SCHEMBL6510243 | 0.89 | ESR1 (0.47) | PPARGPPARAESR1 | |
| SCHEMBL6510237 | 0.89 | ESR1 (0.47) | PPARGPPARAESR1 | |
| SCHEMBL6510322 | 0.86 | PPARG (0.55) | PPARGPPARAESR1SLC7A5LDHA | |
| SCHEMBL6510325 | 0.86 | PPARG (0.55) | PPARGPPARAESR1SLC7A5LDHA | |
| SCHEMBL6511070 | 0.81 | ESR1 (0.48) | PPARGPPARAESR1 | |
| SCHEMBL6511074 | 0.81 | ESR1 (0.48) | PPARGPPARAESR1 | |
| SCHEMBL1487541 | 0.79 | ESR1 (0.54) | PPARGPPARAESR1SLC7A5LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |