Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6502991 | 1.00 | GAA (0.50) | GAAKDM4EMEN1KMT2ALMNA | |
| SCHEMBL6495363 | 0.90 | MAPT (0.48) | GAAKDM4EMEN1KMT2ALMNA | |
| SCHEMBL6495358 | 0.90 | MAPT (0.48) | GAAKDM4EMEN1KMT2ALMNA | |
| SCHEMBL6496834 | 0.84 | GAA (0.54) | GAAKDM4EMEN1KMT2ALMNA | |
| SCHEMBL6505410 | 0.74 | PPARA (0.62) | GAAKDM4E | |
| SCHEMBL3416850 | 0.72 | PSEN1 (0.48) | MEN1KMT2ALMNAPSEN1PSEN2 | |
| SCHEMBL3416847 | 0.72 | PSEN1 (0.48) | MEN1KMT2ALMNAPSEN1PSEN2 | |
| SCHEMBL6504914 | 0.72 | PPARA (0.52) | GAAKDM4EMEN1KMT2ALMNA | |
| SCHEMBL8588648 | 0.72 | GAA (0.58) | GAAKDM4EMEN1KMT2APSEN1 | |
| SCHEMBL21197986 | 0.70 | MEN1 (0.61) | GAAKDM4EMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |