Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14625407 | 1.00 | MAPT (0.38) | MAPTARLMNATSHRALDH1A1 | |
| SCHEMBL8789437 | 1.00 | MAPT (0.38) | MAPTARLMNATSHRALDH1A1 | |
| SCHEMBL438492 | 1.00 | MAPT (0.38) | MAPTARLMNATSHRALDH1A1 | |
| SCHEMBL7621446 | 1.00 | MAPT (0.38) | MAPTARLMNATSHRALDH1A1 | |
| SCHEMBL258503 | 1.00 | MAPT (0.38) | MAPTARLMNATSHRALDH1A1 | |
| SCHEMBL7621444 | 1.00 | MAPT (0.38) | MAPTARLMNATSHRALDH1A1 | |
| SCHEMBL10925441 | 0.98 | MAPT (0.41) | MAPTARLMNATSHRALDH1A1 | |
| SCHEMBL2789219 | 0.95 | — | — | |
| SCHEMBL27274192 | 0.95 | — | — | |
| SCHEMBL25768512 | 0.86 | AR (0.33) | ARCDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005030719-A1 | NOVEL METHOD FOR PREPARING CIS-OCTAHYDRO-ISOINDOLE | LES LABORATOIRES SERVIER (FR) | 2005-04-07 | — | — | WO | claimed |
| WO-2005030719-A1 | NOVEL METHOD FOR PREPARING CIS-OCTAHYDRO-ISOINDOLE | LES LABORATOIRES SERVIER (FR) | 2005-04-07 | — | — | WO | disclosed |
| WO-2005030718-A1 | NOVEL METHOD OF PREPARING CIS-OCTAHYDRO-ISOINDOLE | LES LABORATOIRES SERVIER (FR) | 2005-04-07 | — | — | WO | disclosed |
| EP-0213506-A1 | Saturated cycloalkyl[c]pyrrole-2(1H)-acetic acid amides and derivatives thereof | WARNER-LAMBERT COMPANY (US) | 1987-03-11 | — | — | EP | disclosed |