Ethylene Glycol

Ethylene Glycol

SCHEMBL650353

OCCO.S=C=NCCN=C=S

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MIF P14174 7/20 0.62
TRPA1 O75762 13/20 0.43
NAAA Q02083 1/20 0.42
CYP2E1 P05181 1/20 0.37
CYP2A6 P11509 1/20 0.37
HIF1A Q16665 1/20 0.37
CYP2A13 Q16696 1/20 0.37
EPAS1 Q99814 1/20 0.37
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.36
BACH1 O14867 1/20 0.36
MAFK O60675 1/20 0.36
EGFR P00533 1/20 0.36
PTGS2 P35354 1/20 0.36
KEAP1 Q14145 1/20 0.36
NFE2L2 Q16236 1/20 0.36
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11576485 0.87
SCHEMBL483904 0.86
SCHEMBL18889093 0.81
SCHEMBL5098117 0.79
SCHEMBL5098134 0.77
SCHEMBL3629691 0.77 MIF (1.00) MIFTRPA1NAAAALDH1A1LMNA
SCHEMBL1854857 0.72
SCHEMBL17261552 0.72
SCHEMBL484045 0.72 MIF (0.68) MIFTRPA1NAAAALDH1A1LMNA
Ethylene Glycol SCHEMBL27861985 0.72 MIF (0.39) MIFTRPA1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 185 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240218018-A1 Compstatin Analogs with Increased Solubility and Improved Pharmacokinetic Properties THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2024-07-04 US disclosed
US-11884747-B2 Compstatin analogs with increased solubility and improved pharmacokinetic properties THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2024-01-30 US disclosed
WO-2023178239-A1 HPSC-DERIVED ARTICULAR CHONDROCYTE COMPOSITIONS, SYSTEMS AND METHODS OF USE THEREOF THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2023-09-21 WO disclosed
EP-4011905-A2 COMPSTATIN ANALOGS WITH INCREASED SOLUBILITY AND IMPROVED PHARMACOKINETIC PROPERTIES The Trustees Of The University Of Pennsylvania (US) 2022-06-15 EP disclosed
CN-105582523-B Compstatin and analogs thereof for ocular disorders 阿佩利斯制药公司 2022-04-15 CN disclosed
EP-3645550-B1 COMPSTATIN ANALOGS WITH INCREASED SOLUBILITY AND IMPROVED PHARMACOKINETIC PROPERTIES UNIV PENNSYLVANIA (US) 2021-11-03 EP disclosed
US-11078461-B2 Compositions and methods for implantation of processed adipose tissue and processed adipose tissue products THE JOHNS HOPKINS UNIVERSITY (US) 2021-08-03 US disclosed
CN-112334477-A Compstatin analogs with increased solubility and improved pharmacokinetic properties 宾夕法尼亚大学理事会 2021-02-05 CN disclosed
US-10800812-B2 Compstatin analogs with increased solubility and improved pharmacokinetic properties THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2020-10-13 US disclosed
US-20200188459-A1 PROCESS FOR PREPARING METABOLIZED CONDITIONED GROWTH MEDIA ALLERGAN INC (US) 2020-06-18 US disclosed
WO-2001055212-A2 DELIVERY OF THERAPEUTIC BIOLOGICAL FROM IMPLANTABLE TISSUE MATRICES THE GENERAL HOSPITAL CORPORATION (US) 2001-08-02 WO disclosed
US-6224893-B1 WOUND HEALING AGENT MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2001-05-01 US disclosed
WO-2000069449-A2 CONDITIONED CELL CULTURE MEDIUM COMPOSITIONS AND METHODS OF USE ADVANCED TISSUE SCIENCES, INC. (US) 2000-11-23 WO disclosed
US-6129761-A Injectable hydrogel compositions REPROGENESIS, INC. (US) 2000-10-10 US disclosed
US-6096303-A Method to enhance treatment of cystic tumors MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE, INC. (US) 2000-08-01 US disclosed
EP-1011633-A1 SEMI-INTERPENETRATING OR INTERPENETRATING POLYMER NETWORKS FOR DRUG DELIVERY AND TISSUE ENGINEERING MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2000-06-28 EP disclosed
EP-0938343-A2 TUMOR DELIVERY VEHICLES AND METHOD TO ENHANCE TREATMENT OF CYSTIC TUMORS FBP Corporation (US) 1999-09-01 EP disclosed
US-5945100-A Tumor delivery vehicles FBP CORPORATION (US) 1999-08-31 US disclosed
WO-1998052543-A1 SEMI-INTERPENETRATING OR INTERPENETRATING POLYMER NETWORKS FOR DRUG DELIVERY AND TISSUE ENGINEERING MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1998-11-26 WO disclosed
WO-1998004242-A2 TUMOR DELIVERY VEHICLES AND METHOD TO ENHANCE TREATMENT OF CYSTIC TUMORS FBP CORPORATION (US) 1998-02-05 WO disclosed