Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 15/20 | 0.58 |
| ▸ | NSD2 | O96028 | 3/20 | 0.45 |
| ▸ | APAF1 | O14727 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NQO1 | P15559 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6502756 | 0.90 | NQO2 (0.56) | NQO2NSD2SMARCA2NQO1KEAP1 | |
| SCHEMBL7220854 | 0.89 | NQO2 (0.71) | NQO2NSD2SMARCA2NQO1KEAP1 | |
| SCHEMBL6508268 | 0.86 | NQO2 (0.51) | NQO2NSD2SMARCA2NQO1KEAP1 | |
| SCHEMBL753153 | 0.84 | NQO2 (0.66) | NQO2NSD2SMARCA2NQO1KEAP1 | |
| SCHEMBL13916795 | 0.84 | NQO2 (0.68) | NQO2NSD2SMARCA2NQO1KEAP1 | |
| SCHEMBL13916807 | 0.81 | NQO2 (0.64) | NQO2NSD2SMARCA2NQO1KEAP1 | |
| SCHEMBL753152 | 0.81 | NQO2 (0.61) | NQO2NSD2SMARCA2NQO1KEAP1 | |
| SCHEMBL7062442 | 0.77 | NQO2 (0.52) | NQO2NSD2MAPTRAB9ANPSR1 | |
| SCHEMBL13928512 | 0.76 | NQO2 (0.76) | NQO2NSD2SMARCA2NQO1KEAP1 | |
| SCHEMBL29406123 | 0.75 | NQO2 (0.49) | NQO2NSD2MAPTHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050032794-A1 | Diamine derivatives of quinone and uses thereof | CLINICAL DATA, INC. | 2005-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050032794-A1 | Diamine derivatives of quinone and uses thereof | NQO1, DPYD, NQO2 | NQO2 3/4885NSD2 609/4885APAF1 3860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.